Effects of free fatty acids on sodium currents in rat dorsal root ganglion neurons

Free fatty acids (FFAs), especially polyunsaturated fatty acids (PUFAs), are potent modulators of muscle-type sodium channels. It is not known if they also modulate sodium channels of sensory neurons. In this study, we investigated the effects of FFAs on the fast tetrodotoxin-sensitive (fTTX-S) and...

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Veröffentlicht in:	Brain research 2004-05, Vol.1008 (1), p.81-91
Hauptverfasser:	Hong, Min-Pyo, Kim, Hong Im, Shin, Yong Kyoo, Lee, Chung Soo, Park, Mijung, Song, Jin-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences Cells, Cultured Central nervous system Dorsal root ganglion Dose-Response Relationship, Drug Electric Conductivity Electrophysiology Fatty Acids - pharmacology Free fatty acid Fundamental and applied biological sciences. Psychology Ganglia, Spinal - cytology Ion Channel Gating - drug effects Membrane Potentials - drug effects Neurons - classification Neurons - drug effects Neurons - physiology Patch-Clamp Techniques - methods Rats Sodium - metabolism Sodium Channel Blockers - pharmacology Sodium Channels - drug effects Sodium Channels - physiology Sodium current Tetrodotoxin - pharmacology Tetrodotoxin-resistant Tetrodotoxin-sensitive Vertebrates: nervous system and sense organs
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