Involvement of an SCF super(Slmb) complex in timely elimination of E2F upon initiation of DNA replication in Drosophila

Cul1 is a core component of the evolutionarily conserved SCF-type ubiquitin ligases that target specific proteins for destruction. SCF action contributes to cell cycle progression but few of the key targets of its action have been identified. We found that expression of the mouse Cul1 (mCul1) in the...

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Veröffentlicht in:BMC genetics 2003-01, Vol.4
Hauptverfasser: Heriche, Jean-Karim, Ang, Dan, Bier, Ethan, OFarrell, Patrick H
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Sprache:eng
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