Rapid Biomonitoring of Heterocyclic Aromatic Amines in Human Urine by Tandem Solvent Solid Phase Extraction Liquid Chromatography Electrospray Ionization Mass Spectrometry

A rapid and facile tandem solvent solid phase extraction method was established to isolate the heterocyclic aromatic amines (HAAs) 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (8-MeIQx), 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and 2-amino-9...

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Veröffentlicht in:	Chemical research in toxicology 2004-08, Vol.17 (8), p.1121-1136
Hauptverfasser:	Holland, Ricky D, Taylor, Jason, Schoenbachler, Laura, Jones, Richard C, Freeman, James P, Miller, Dwight W, Lake, Brian G, Gooderham, Nigel J, Turesky, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines - urine Animals Carbolines - urine Cattle Chromatography, Liquid - methods Food - toxicity Heterocyclic Compounds - adverse effects Heterocyclic Compounds - urine Humans Male Polycyclic Aromatic Hydrocarbons - adverse effects Polycyclic Aromatic Hydrocarbons - urine Quinoxalines - urine Spectrometry, Mass, Electrospray Ionization - methods
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