Associations between physical activity and bone mass in black and white South African children at age 9 yr

1 Medical Research Council Mineral Metabolism Research Unit, Department of Paediatrics, University of Witwatersrand, and 2 School of Physiology, University of Witwatersrand Medical School, Parktown, Gauteng 2193, South Africa; and 3 Department of Human Biology, University of Loughborough, Leicestershire LE11 3TU, United Kingdom Submitted 20 January 2004 ; accepted in final form 4 May 2004 We investigated differences in physical activity (PA) levels between black and white South African 9-yr-old children and their association with bone mineral content (BMC) and density (BMD) by using dual-energy X-ray absorptiometry. PA was analyzed in terms of a metabolic (METPA; weighted metabolic score of intensity, frequency, and duration) and a mechanical (MECHPA; sum of all ground reaction forces multiplied by duration) component. There were significant ethnic differences in patterns of activity. White children expended a significantly greater energy score (METPA of 21.7 ± 2.9) than black children (METPA of 9.5 ± 0.5) ( P < 0.001). When children were divided into quartiles according to the amount and intensity of sport played, the most active white children (using METPA scores) had significantly higher whole body BMD and higher hip and spine BMC and BMD than less active children. White children in the highest MECHPA quartile also showed significantly higher whole body, hip, and spine BMC and BMD than those children in the lowest quartile. No association between exercise and bone mass of black children was found. In this population, PA has an osteogenic association with white children, but not black children, which may be explained by the lower levels of PA in the black children. Despite this, black children had significantly greater bone mass at the hip and spine (girls only) ( P < 0.001) even after adjustment for body size. The role of exercise in increasing bone mass may become increasingly critical as a protective mechanism against osteoporosis in both ethnic groups, especially because the genetic benefit exhibited by black children to higher bone mass may be weakened with time, as environmental influences become stronger. bone mass; South Africa; ethnicity Address for reprint requests and other correspondence: J. A. McVeigh, School of Physiology, Univ. of the Witwatersrand Medical School, 7 York Rd., Parktown, Gauteng 2193, South Africa (E-mail: mcveighja{at}physiology.wits.ac.za ).