Pharmacological effects and toxicity of Costus pulverulentus C. Presl (Costaceae)

Costus pulverulentus C. Presl (Costaceae), a species endemic to Mexico, is used for the empirical treatment of cancer, pain, and inflammation. The objective of this study was to evaluate the toxicity, as well as the cytotoxic, antinociceptive, anti-inflammatory and sedative effects of an ethanol ext...

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Veröffentlicht in:	Journal of ethnopharmacology 2016-03, Vol.180, p.124-130
Hauptverfasser:	Alonso-Castro, Angel Josabad, Zapata-Morales, Juan Ramón, González-Chávez, Marco Martin, Carranza-Álvarez, Candy, Hernández-Benavides, Diego Manuel, Hernández-Morales, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid Analgesics - pharmacology Analgesics - therapeutic use Analgesics - toxicity Anesthetics, Dissociative - pharmacology Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Anti-Inflammatory Agents - toxicity Antiinflammatory Antinociceptive Cancer Cell Line, Tumor Cell Survival - drug effects Comet Assay Costaceae Costus Costus pulverulentus Edema - drug therapy Formaldehyde Gas chromatography–mass spectrometry Hot Temperature Humans Ketamine - pharmacology Lethal Dose 50 Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Male Mice, Inbred BALB C Pain - chemically induced Pain - drug therapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Extracts - toxicity Plant Stems Toxicity
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