SYNTHESIS, CHARACTERIZATION OF NOVEL MIXED METAL TARTRATEC OMPLEXES AND STUDY OF THEIR IN VITRO ANTIMICROBIAL ACTIVITY

A series of six new mixed metal complexes of general formulation (MM12(L)n)xH2O, where M = Mn, Co, Ni, Cu, Zn, Cd, M1 = Fe, L = Tartrate ligand, x = 1, 5, 6 and n = 3, are synthesized using tartrate as a bidented ligand. The newly synthesized complexes were characterized using various analytical tec...

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Veröffentlicht in:International journal of pharmaceutical sciences and research 2016-04, Vol.7 (4), p.1524-1524
Hauptverfasser: Patil, C S, Dhavale, N S, Tadke, V B, Pawar, R P
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Sprache:eng
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Zusammenfassung:A series of six new mixed metal complexes of general formulation (MM12(L)n)xH2O, where M = Mn, Co, Ni, Cu, Zn, Cd, M1 = Fe, L = Tartrate ligand, x = 1, 5, 6 and n = 3, are synthesized using tartrate as a bidented ligand. The newly synthesized complexes were characterized using various analytical techniques such as IR, XRD, TGA, Elemental analysis, magnetic susceptibility study etc. IR spectral data suggested that the bidentate ligand has coordination to both the metal ions through oxygen as donor atoms. The thermal behavior (TGA) of the complexes was studied; suggest the decomposition patterns were in good agreement with recommended formulae of the complexes. XRD technique revealed the presence of crystalline nature of all the studied complexes. The antibacterial activity of the metal complexes along with ligand was assayed against three bacterial pathogens viz. Bacillus Megatherium, Staphylococcus aureus, E-Coli, Pseudomonas and Proteus Vulgaris by well diffusion method.
ISSN:0975-8232
DOI:10.13040/IJPSR.0975-8232.7(4).1524-34