The Ca super(2+) Homeostasis Defects in a pgm2delta Strain of Saccharomyces cerevisiae Are Caused by Excessive Vacuolar Ca super(2+) Uptake Mediated by the Ca super(2+)-ATPase Pmc1p
Loss of the major isoform of phosphoglucomutase (PGM) causes an accumulation of glucose 1-phosphate when yeast cells are grown with galactose as the carbon and energy source. Remarkably, the pgm2delta strain also exhibits a severe imbalance in intracellular Ca super(2+) homeostasis when grown under...
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Veröffentlicht in: | The Journal of biological chemistry 2004-09, Vol.279 (37), p.38495-38502 |
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