Formulation and stabilization of norfloxacin in liposomal preparations

A number of liposomal preparations of norfloxacin (NF) containing variable concentrations of phosphatidylcholine (PC) (10.8–16.2mM) have been formulated and an entrapment of NF to the extent of 41.7–56.2% was achieved. The values of apparent first-order rate constants (kobs) for the photodegradation...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2016-08, Vol.91, p.208-215
Hauptverfasser:	Ahmad, Iqbal, Arsalan, Adeel, Ali, Syed Abid, Bano, Raheela, Munir, Iqra, Sabah, Arif
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - radiation effects Charge-transfer complex Chemistry, Pharmaceutical Chromatography, High Pressure Liquid Drug Stability Hydrogen-Ion Concentration Kinetics Light Liposomal preparation Liposomes Norfloxacin Norfloxacin - chemistry Norfloxacin - radiation effects Phosphatidylcholines - chemistry Photodegradation Photolysis Spectrometry, Fluorescence Stabilization
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