A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium

The Cdk8 proteins are kinases which phosphorylate the carboxy terminal domain (CTD) of RNA polymerase II (Pol II) as well as some transcription factors and, therefore, are involved in the regulation of transcription. Here, we report that a Cdk8 homologue from Dictyostelium discoideum is localized in...

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Veröffentlicht in:	Developmental biology 2004-07, Vol.271 (1), p.49-58
Hauptverfasser:	Lin, Hsiu-Hsu Sophia, Khosla, Meenal, Huang, Hao-Jen, Hsu, Duen-Wei, Michaelis, Christine, Weeks, Gerald, Pears, Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta-Galactosidase Blotting, Northern Chemotaxis - physiology Chromatography, Gel CTD phosphorylation Dictyostelium - enzymology Dictyostelium - growth & development Dictyostelium discoideum Fluorescent Antibody Technique Gene Expression Regulation, Developmental Gene Library Mutagenesis, Insertional Phenotype Precipitin Tests Regulation of transcription RNA polymerase II Sequence Analysis, DNA Spore differentiation Spores - growth & development Transfection
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