Reducing Spatial Heterogeneity of MALDI Samples with Marangoni Flows During Sample Preparation

This work demonstrates a method to prepare homogeneous distributions of analytes to improve data reproducibility in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS). Natural-air drying processes normally result in unwanted heterogeneous spatial distributions of analytes in...

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Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2016-08, Vol.27 (8), p.1314-1321
Hauptverfasser:	Lai, Yin-Hung, Cai, Yi-Hong, Lee, Hsun, Ou, Yu-Meng, Hsiao, Chih-Hao, Tsao, Chien-Wei, Chang, Huan-Tsung, Wang, Yi-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Air drying Analytical Chemistry Bioinformatics Biomolecules Biotechnology Chemistry Chemistry and Materials Science Desorption Droplets Heterogeneity Ionization Ions Mass spectrometry Organic Chemistry Proteomics Quantitative analysis Reproducibility Research Article Scientific imaging Spectroscopy Temperature gradients
Online-Zugang:	Volltext
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