Design of iron oxide-based nanoparticles for MRI and magnetic hyperthermia
Iron oxide nanoparticles are widely used for biological applications thanks to their outstanding balance between magnetic properties, surface-to-volume ratio suitable for efficient functionalization and proven biocompatibility. Their development for MRI or magnetic particle hyperthermia concentrates...
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| Veröffentlicht in: | Nanomedicine (London, England) England), 2016-07, Vol.11 (14), p.1889-1910 |
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| container_title | Nanomedicine (London, England) |
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| creator | Blanco-Andujar, Cristina Walter, Aurelie Cotin, Geoffrey Bordeianu, Catalina Mertz, Damien Felder-Flesch, Delphine Begin-Colin, Sylvie |
| description | Iron oxide nanoparticles are widely used for biological applications thanks to their outstanding balance between magnetic properties, surface-to-volume ratio suitable for efficient functionalization and proven biocompatibility. Their development for MRI or magnetic particle hyperthermia concentrates much of the attention as these nanomaterials are already used within the health system as contrast agents and heating mediators. As such, the constant improvement and development for better and more reliable materials is of key importance. On this basis, this review aims to cover the rational design of iron oxide nanoparticles to be used as MRI contrast agents or heating mediators in magnetic hyperthermia, and reviews the state of the art of their use as nanomedicine tools. |
| doi_str_mv | 10.2217/nnm-2016-5001 |
| format | Article |
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Their development for MRI or magnetic particle hyperthermia concentrates much of the attention as these nanomaterials are already used within the health system as contrast agents and heating mediators. As such, the constant improvement and development for better and more reliable materials is of key importance. 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| subjects | Animals Apoptosis Biomedical materials Cancer therapies Contrast Media - chemistry Contrast Media - therapeutic use Evolution Fever Humans Hyperthermia Hyperthermia, Induced - methods iron oxide Magnetic fields magnetic hyperthermia Magnetic Resonance Imaging - methods Magnetite Nanoparticles - chemistry Magnetite Nanoparticles - therapeutic use MRI Nanoparticles Nanotechnology NMR Nuclear magnetic resonance Radiation therapy Tumors |
| title | Design of iron oxide-based nanoparticles for MRI and magnetic hyperthermia |
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