Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

Summary Background Severe asthma is a complex heterogeneous disease associated with older age and obesity. The presence of eosinophilic (type 2) inflammation in some but not all patients with severe asthma predicts responsiveness to current treatments, but new treatment approaches will require a bet...

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Veröffentlicht in:	The lancet respiratory medicine 2016-07, Vol.4 (7), p.574-584
Hauptverfasser:	Peters, Michael C, MD, McGrath, Kelly Wong, MS, Hawkins, Gregory A, PhD, Hastie, Annette T, PhD, Levy, Bruce D, MD, Israel, Elliot, MD, Phillips, Brenda R, MS, Mauger, David T, PhD, Comhair, Suzy A, PhD, Erzurum, Serpil C, MD, Johansson, Mats W, PhD, Jarjour, Nizar N, MD, Coverstone, Andrea M, MD, Castro, Mario, MD, Holguin, Fernando, MD, Wenzel, Sally E, MD, Woodruff, Prescott G, MD, Bleecker, Eugene R, MD, Fahy, John V, Dr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asthma - blood Asthma - complications Asthma - physiopathology Cohort Studies Cross-Sectional Studies Disease Progression Female Forced Expiratory Volume Humans Inflammation Interleukin-6 - blood Lung - physiopathology Male Middle Aged Obesity - blood Obesity - complications Obesity - physiopathology Pulmonary/Respiratory Severity of Illness Index
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