REN super(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

Hedgehog signaling is suggested to be a major oncogenic pathway in medulloblastoma, which arises from aberrant development of cerebellar granule progenitors. Allelic loss of chromosome 17p has also been described as the most frequent genetic defect in this human neoplasia. This observation raises th...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-07, Vol.101 (29), p.10833-10838
Hauptverfasser:	Di Marcotullio, Lucia, Ferretti, Elisabetta, De Smaele, Enrico, Argenti, Beatrice, Mincione, Claudia, Zazzeroni, Francesca, Gallo, Rita, Masuelli, Laura, Napolitano, Maddalena, Maroder, Marella, Modesti, Andrea, Giangaspero, Felice, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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