Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects

In previous studies, it has been shown that both simvastatin (chlolesterollowering drug) and platelet-rich plasma (PRP) were capable of promoting bone formation. The aim of this study was to compare the effects of PRP and simvastatin on healing of critical-size bone defects. A total of 33 rats (3 fo...

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Veröffentlicht in:	The Journal of craniofacial surgery 2016-07, Vol.27 (5), p.1367-1370
Hauptverfasser:	Seyhan, Nevra, Keskin, Suat, Aktan, Murat, Avunduk, Mustafa Cihad, Sengelen, Meltem, Savaci, Nedim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Diseases - diagnosis Bone Diseases - therapy Bone Regeneration - drug effects Dentistry Disease Models, Animal Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Osteoblasts - pathology Osteogenesis - drug effects Platelet-Rich Plasma Rats Simvastatin - pharmacology Skull - injuries Skull - surgery Wound Healing - drug effects
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