Novel Approach of Treatment of Pilonidal Sinus Disease With Thrombin Gelatin Matrix as a Sealant
BACKGROUND:Sacrococcygeal pilonidal sinus disease is a condition caused by insertion of fallen hair shafts into the skin. Different types of operations have been described for the management of pilonidal sinus, yet none of them have proven to be superior to the others. Recently, sealants like fibrin...
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| Veröffentlicht in: | Diseases of the colon & rectum 2016-08, Vol.59 (8), p.775-780 |
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| container_title | Diseases of the colon & rectum |
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| creator | Elbanna, Hosam G Emile, Sameh Hany Youssef, Mohamed Thabet, Waleed El-Hamed, Tito M Abd Ghnnam, Wagih M |
| description | BACKGROUND:Sacrococcygeal pilonidal sinus disease is a condition caused by insertion of fallen hair shafts into the skin. Different types of operations have been described for the management of pilonidal sinus, yet none of them have proven to be superior to the others. Recently, sealants like fibrin glue have been successfully used.
OBJECTIVE:This study aimed to assess the efficacy of thrombin gelatin matrix as a new sealant for pilonidal sinus treatment.
DESIGN:This was a prospective study conducted from March 2013 to March 2015.
SETTINGS:The study was conducted in private hospitals in Mansoura City.
PATIENTS:The study included 36 male patients (72%) and 14 female patients (28%), with a median age of 22 years.
INTERVENTIONS:Fifty patients with pilonidal sinus were admitted and treated with thrombin gelatin matrix injection.
MAIN OUTCOME MEASURES:Incidence and time of pilonidal sinus recurrence, postoperative pain and complications, duration of hospital stay, healing status, and time to return to work were recorded.
RESULTS:The median duration of symptoms was 13 months, median operative time was 18 minutes, and median hospital stay was 6 hours. All of the procedures were conducted as day-case surgeries. Median follow-up duration was 24 months. Three patients (6%) had a breakdown of the sealant, and the wound was managed with daily dressings. Recurrence at 1 year was observed in 2 patients (4%). A total of 96% of patients were satisfied with the outcome of the procedure, and 92% of patients resumed their daily activities within 3 days.
LIMITATIONS:Follow-up for a longer duration is required to ascertain the efficacy of this new technique. The cost of this treatment might be challenging for resource-limited communities.
CONCLUSIONS:Management of pilonidal sinus using thrombin gelatin matrix, despite being expensive, is an effective, simple treatment that is easy to perform and associated with low recurrence rate, minimal morbidity, and rapid recovery. |
| doi_str_mv | 10.1097/DCR.0000000000000604 |
| format | Article |
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OBJECTIVE:This study aimed to assess the efficacy of thrombin gelatin matrix as a new sealant for pilonidal sinus treatment.
DESIGN:This was a prospective study conducted from March 2013 to March 2015.
SETTINGS:The study was conducted in private hospitals in Mansoura City.
PATIENTS:The study included 36 male patients (72%) and 14 female patients (28%), with a median age of 22 years.
INTERVENTIONS:Fifty patients with pilonidal sinus were admitted and treated with thrombin gelatin matrix injection.
MAIN OUTCOME MEASURES:Incidence and time of pilonidal sinus recurrence, postoperative pain and complications, duration of hospital stay, healing status, and time to return to work were recorded.
RESULTS:The median duration of symptoms was 13 months, median operative time was 18 minutes, and median hospital stay was 6 hours. All of the procedures were conducted as day-case surgeries. Median follow-up duration was 24 months. Three patients (6%) had a breakdown of the sealant, and the wound was managed with daily dressings. Recurrence at 1 year was observed in 2 patients (4%). A total of 96% of patients were satisfied with the outcome of the procedure, and 92% of patients resumed their daily activities within 3 days.
LIMITATIONS:Follow-up for a longer duration is required to ascertain the efficacy of this new technique. The cost of this treatment might be challenging for resource-limited communities.
CONCLUSIONS:Management of pilonidal sinus using thrombin gelatin matrix, despite being expensive, is an effective, simple treatment that is easy to perform and associated with low recurrence rate, minimal morbidity, and rapid recovery.</description><identifier>ISSN: 0012-3706</identifier><identifier>EISSN: 1530-0358</identifier><identifier>DOI: 10.1097/DCR.0000000000000604</identifier><identifier>PMID: 27384096</identifier><language>eng</language><publisher>United States: The American Society of Colon and Rectal Surgeons</publisher><subject>Adolescent ; Adult ; Curettage ; Female ; Follow-Up Studies ; Gelatin - therapeutic use ; Humans ; Male ; Middle Aged ; Pilonidal Sinus - surgery ; Prospective Studies ; Recurrence ; Thrombin - therapeutic use ; Tissue Adhesives - therapeutic use ; Treatment Outcome ; Young Adult</subject><ispartof>Diseases of the colon & rectum, 2016-08, Vol.59 (8), p.775-780</ispartof><rights>2016 The American Society of Colon and Rectal Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3521-b602f4c29a923c74cf4e5d0bfb5ba27c390935afeb3d1e3c59aac973e51809b73</citedby><cites>FETCH-LOGICAL-c3521-b602f4c29a923c74cf4e5d0bfb5ba27c390935afeb3d1e3c59aac973e51809b73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27384096$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elbanna, Hosam G</creatorcontrib><creatorcontrib>Emile, Sameh Hany</creatorcontrib><creatorcontrib>Youssef, Mohamed</creatorcontrib><creatorcontrib>Thabet, Waleed</creatorcontrib><creatorcontrib>El-Hamed, Tito M Abd</creatorcontrib><creatorcontrib>Ghnnam, Wagih M</creatorcontrib><title>Novel Approach of Treatment of Pilonidal Sinus Disease With Thrombin Gelatin Matrix as a Sealant</title><title>Diseases of the colon & rectum</title><addtitle>Dis Colon Rectum</addtitle><description>BACKGROUND:Sacrococcygeal pilonidal sinus disease is a condition caused by insertion of fallen hair shafts into the skin. Different types of operations have been described for the management of pilonidal sinus, yet none of them have proven to be superior to the others. Recently, sealants like fibrin glue have been successfully used.
OBJECTIVE:This study aimed to assess the efficacy of thrombin gelatin matrix as a new sealant for pilonidal sinus treatment.
DESIGN:This was a prospective study conducted from March 2013 to March 2015.
SETTINGS:The study was conducted in private hospitals in Mansoura City.
PATIENTS:The study included 36 male patients (72%) and 14 female patients (28%), with a median age of 22 years.
INTERVENTIONS:Fifty patients with pilonidal sinus were admitted and treated with thrombin gelatin matrix injection.
MAIN OUTCOME MEASURES:Incidence and time of pilonidal sinus recurrence, postoperative pain and complications, duration of hospital stay, healing status, and time to return to work were recorded.
RESULTS:The median duration of symptoms was 13 months, median operative time was 18 minutes, and median hospital stay was 6 hours. All of the procedures were conducted as day-case surgeries. Median follow-up duration was 24 months. Three patients (6%) had a breakdown of the sealant, and the wound was managed with daily dressings. Recurrence at 1 year was observed in 2 patients (4%). A total of 96% of patients were satisfied with the outcome of the procedure, and 92% of patients resumed their daily activities within 3 days.
LIMITATIONS:Follow-up for a longer duration is required to ascertain the efficacy of this new technique. The cost of this treatment might be challenging for resource-limited communities.
CONCLUSIONS:Management of pilonidal sinus using thrombin gelatin matrix, despite being expensive, is an effective, simple treatment that is easy to perform and associated with low recurrence rate, minimal morbidity, and rapid recovery.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Curettage</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gelatin - therapeutic use</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pilonidal Sinus - surgery</subject><subject>Prospective Studies</subject><subject>Recurrence</subject><subject>Thrombin - therapeutic use</subject><subject>Tissue Adhesives - therapeutic use</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0012-3706</issn><issn>1530-0358</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkN1u1DAQhS0EokvhDRDyJTcpYzuO15fVlhakAhVdxGWYeCeKwUkW22nh7XFp-VFHGo2OdObY8zH2XMCRAGtenWw-HsH_1UD9gK2EVlCB0uuHbAUgZKUMNAfsSUpfiwQJ5jE7kEata7DNin15P19R4Mf7fZzRDXzu-TYS5pGmfCMufJgnv8PAL_20JH7iE2Ei_tnngW-HOI-dn_gZBcxlvsMc_Q-OiSO_JAw45afsUY8h0bO7ecg-nb7ebt5U5x_O3m6OzyuntBRV14DsayctWqmcqV1fk95B13e6Q2mcsmCVxp46tROknLaIzhpFWqzBdkYdspe3ueWQ7wul3I4-OQrlDzQvqS22crXWpinW-tbq4pxSpL7dRz9i_NkKaG_YtoVte59tWXtx98LSjbT7u_QH5r_c6zlkiulbWK4ptkMBkYffearWqpIgGlgXVZUWQv0CUI6DfA</recordid><startdate>201608</startdate><enddate>201608</enddate><creator>Elbanna, Hosam G</creator><creator>Emile, Sameh Hany</creator><creator>Youssef, Mohamed</creator><creator>Thabet, Waleed</creator><creator>El-Hamed, Tito M Abd</creator><creator>Ghnnam, Wagih M</creator><general>The American Society of Colon and Rectal Surgeons</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201608</creationdate><title>Novel Approach of Treatment of Pilonidal Sinus Disease With Thrombin Gelatin Matrix as a Sealant</title><author>Elbanna, Hosam G ; Emile, Sameh Hany ; Youssef, Mohamed ; Thabet, Waleed ; El-Hamed, Tito M Abd ; Ghnnam, Wagih M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3521-b602f4c29a923c74cf4e5d0bfb5ba27c390935afeb3d1e3c59aac973e51809b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Curettage</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gelatin - therapeutic use</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pilonidal Sinus - surgery</topic><topic>Prospective Studies</topic><topic>Recurrence</topic><topic>Thrombin - therapeutic use</topic><topic>Tissue Adhesives - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elbanna, Hosam G</creatorcontrib><creatorcontrib>Emile, Sameh Hany</creatorcontrib><creatorcontrib>Youssef, Mohamed</creatorcontrib><creatorcontrib>Thabet, Waleed</creatorcontrib><creatorcontrib>El-Hamed, Tito M Abd</creatorcontrib><creatorcontrib>Ghnnam, Wagih M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diseases of the colon & rectum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elbanna, Hosam G</au><au>Emile, Sameh Hany</au><au>Youssef, Mohamed</au><au>Thabet, Waleed</au><au>El-Hamed, Tito M Abd</au><au>Ghnnam, Wagih M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel Approach of Treatment of Pilonidal Sinus Disease With Thrombin Gelatin Matrix as a Sealant</atitle><jtitle>Diseases of the colon & rectum</jtitle><addtitle>Dis Colon Rectum</addtitle><date>2016-08</date><risdate>2016</risdate><volume>59</volume><issue>8</issue><spage>775</spage><epage>780</epage><pages>775-780</pages><issn>0012-3706</issn><eissn>1530-0358</eissn><abstract>BACKGROUND:Sacrococcygeal pilonidal sinus disease is a condition caused by insertion of fallen hair shafts into the skin. Different types of operations have been described for the management of pilonidal sinus, yet none of them have proven to be superior to the others. Recently, sealants like fibrin glue have been successfully used.
OBJECTIVE:This study aimed to assess the efficacy of thrombin gelatin matrix as a new sealant for pilonidal sinus treatment.
DESIGN:This was a prospective study conducted from March 2013 to March 2015.
SETTINGS:The study was conducted in private hospitals in Mansoura City.
PATIENTS:The study included 36 male patients (72%) and 14 female patients (28%), with a median age of 22 years.
INTERVENTIONS:Fifty patients with pilonidal sinus were admitted and treated with thrombin gelatin matrix injection.
MAIN OUTCOME MEASURES:Incidence and time of pilonidal sinus recurrence, postoperative pain and complications, duration of hospital stay, healing status, and time to return to work were recorded.
RESULTS:The median duration of symptoms was 13 months, median operative time was 18 minutes, and median hospital stay was 6 hours. All of the procedures were conducted as day-case surgeries. Median follow-up duration was 24 months. Three patients (6%) had a breakdown of the sealant, and the wound was managed with daily dressings. Recurrence at 1 year was observed in 2 patients (4%). A total of 96% of patients were satisfied with the outcome of the procedure, and 92% of patients resumed their daily activities within 3 days.
LIMITATIONS:Follow-up for a longer duration is required to ascertain the efficacy of this new technique. The cost of this treatment might be challenging for resource-limited communities.
CONCLUSIONS:Management of pilonidal sinus using thrombin gelatin matrix, despite being expensive, is an effective, simple treatment that is easy to perform and associated with low recurrence rate, minimal morbidity, and rapid recovery.</abstract><cop>United States</cop><pub>The American Society of Colon and Rectal Surgeons</pub><pmid>27384096</pmid><doi>10.1097/DCR.0000000000000604</doi><tpages>6</tpages></addata></record> |
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| ispartof | Diseases of the colon & rectum, 2016-08, Vol.59 (8), p.775-780 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Adult Curettage Female Follow-Up Studies Gelatin - therapeutic use Humans Male Middle Aged Pilonidal Sinus - surgery Prospective Studies Recurrence Thrombin - therapeutic use Tissue Adhesives - therapeutic use Treatment Outcome Young Adult |
| title | Novel Approach of Treatment of Pilonidal Sinus Disease With Thrombin Gelatin Matrix as a Sealant |
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