Evaluation of [89Zr]-Oxalate as a PET Tracer in Inflammation, Tumor, and Rheumatoid Arthritis Models

To obtain an additional pharmacological agent for the diagnosis of inflammation, we investigated the medical use of 89Zr-oxalate as a positron emission tomography (PET) probe for the in vivo imaging of inflammation and compared its efficacy to that of 2-deoxy-2-[18F]­fluoro-d-glucose ([18F]­FDG) and...

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Veröffentlicht in:	Molecular pharmaceutics 2016-07, Vol.13 (7), p.2571-2577
Hauptverfasser:	Park, Ji-Ae, Lee, Yong Jin, Lee, Ji Woong, Yoo, Ran Ji, Shin, Un Chol, Lee, Kyo Chul, Kim, Byung il, Kim, Kyeong Min, Kim, Jung Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Rheumatoid - diagnostic imaging Cell Line, Tumor Fluorodeoxyglucose F18 - analysis Fluorodeoxyglucose F18 - chemistry Humans Inflammation - diagnostic imaging Male Mice Oxalates - analysis Oxalates - chemistry Positron-Emission Tomography - methods RAW 264.7 Cells
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