Selective Recognition of G-Quadruplex Telomeric DNA by a Bis(quinacridine) Macrocycle

The interaction of G-quadruplex DNA with the macrocyclic compound BOQ1, which possesses two dibenzophenanthroline (quinacridine) subunits, has been investigated by a variety of methods. The oligonucleotide 5‘-A(GGGT2A)3G3, which mimics the human telomeric repeat sequence and forms an intramolecular...

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Veröffentlicht in:Journal of the American Chemical Society 2003-04, Vol.125 (16), p.4732-4740
Hauptverfasser: Teulade-Fichou, Marie-Paule, Carrasco, Carolina, Guittat, Lionel, Bailly, Christian, Alberti, Patrizia, Mergny, Jean-Louis, David, Arnaud, Lehn, Jean-Marie, Wilson, W. David
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Sprache:eng
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