Isolation of Adda from microcystin-LR by microbial degradation

The intact Adda was isolated from microcystin-LR by a microbial degradation using an isolated Sphingomonas strain, B-9. The reaction of microcystin-LR with cell extract of this strain proceeded smoothly to give the final degradation product by way of two intermediates, linearized microcystin-LR and...

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Veröffentlicht in:	Toxicon (Oxford) 2004-07, Vol.44 (1), p.107-109
Hauptverfasser:	Harada, Ken-ichi, Imanishi, Susumu, Kato, Hajime, Mizuno, Masayoshi, Ito, Emiko, Tsuji, Kiyomi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adda Amino Acids - chemistry Amino Acids - isolation & purification Bacterial Toxins - metabolism Bacteriology Biodegradation, Environmental Biological and medical sciences Cyanobacteria - chemistry Fundamental and applied biological sciences. Psychology Magnetic Resonance Spectroscopy Marine Toxins - metabolism Microbial degradation Microbiology Microcystin Microcystins Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Peptides, Cyclic - chemistry Peptides, Cyclic - metabolism Sphingomonas Sphingomonas - metabolism Toxicity
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