Novel RIPK3 inhibitors discovered through a structure-based approach exert post-ischemic neuroprotection
Necroptosis or programmed necrosis is evident in various neurological disorders such as ischemic stroke. Receptor interacting serine/threonine protein kinase 3 (RIPK3) is one of the crucial targets of necroptosis and inhibition of this protein exerts neuroprotection. However, knowledge regarding the...
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Veröffentlicht in: | Molecular diversity 2016-08, Vol.20 (3), p.719-728 |
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