Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

To elucidate the relationship between tumorgenesis and the mitochondrial energy metabolism in renal neoplasms, we studied three individual enzyme activities of the oxidative phosphorylation, two components of the Krebs cycle and the mitochondrial DNA content of renal carcinomas including 29 conventi...

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Veröffentlicht in:	Carcinogenesis (New York) 2004-06, Vol.25 (6), p.1005-1010
Hauptverfasser:	Meierhofer, David, Mayr, Johannes A., Foetschl, Ulrike, Berger, Alexandra, Fink, Klaus, Schmeller, Nikolaus, Hacker, Gerhard W., Hauser-Kronberger, Cornelia, Kofler, Barbara, Sperl, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Blotting, Western Carcinogenesis, carcinogens and anticarcinogens Carcinoma, Renal Cell - metabolism COX cytochrome c oxidase DNA, Mitochondrial - metabolism Energy Metabolism Female Humans Immunohistochemistry Kidney Neoplasms - metabolism m/r ratio Male Medical sciences Middle Aged oxidative phosphorylation OXPHOS relative ratio of mitochondrial DNA to 18S rDNA Tumors
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