The chloride channel inhibitor N53736 prevents bone resorption in ovariectomized rats without changing bone formation

Chloride channel activity is essential for osteoclast function. Consequently, inhibition of the osteoclastic chloride channel should prevent bone resorption. Accordingly, we tested a chloride channel inhibitor on bone turnover and found that it inhibits bone resorption without affecting bone formati...

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Veröffentlicht in:	Journal of bone and mineral research 2004-07, Vol.19 (7), p.1144-1153
Hauptverfasser:	SCHALLER, Sophie, HENRIKSEN, Kim, HOUGAARD, Dorit, BERRYMAN, Mark, SHIODT, Christine B, SØRENSEN, Bjørn H, LICHTENBERG, Jens, CHRISTOPHERSEN, Palle, FOGED, Niels T, DELAISSE, Jean-Marie, ENGSIG, Michael T, KARSDAL, Morten A, SVEIGAARD, Christina, HEEGAARD, Anne-Marie, HELIX, Nathalie, STAHLHUT, Martin, OVEJERO, Maria C, JOHANSEN, Jens V, SOLBERG, Helene, ANDERSEN, Thomas L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Fundamental and applied biological sciences. Psychology Skeleton and joints Vertebrates: osteoarticular system, musculoskeletal system
Online-Zugang:	Volltext
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