Early symptoms of Alzheimer's disease in Japan and Taiwan
Aim The effects of Alzheimer's disease (AD) are making a major impact on the socioeconomic status of older adults in society. The recognition of early symptoms and clinical presentation are crucial issues to foster early diagnosis and treatment in order to have better therapeutic outcomes. Meth...
Gespeichert in:
| Veröffentlicht in: | Geriatrics & gerontology international 2016-07, Vol.16 (7), p.797-803 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 803 |
|---|---|
| container_issue | 7 |
| container_start_page | 797 |
| container_title | Geriatrics & gerontology international |
| container_volume | 16 |
| creator | Yang, Yuan-Han Hsu, Chia-Ling Chou, Mei-Chuan Kasai, Mari Meguro, Kenichi Liu, Ching-Kuan |
| description | Aim
The effects of Alzheimer's disease (AD) are making a major impact on the socioeconomic status of older adults in society. The recognition of early symptoms and clinical presentation are crucial issues to foster early diagnosis and treatment in order to have better therapeutic outcomes.
Methods
We recruited clinically diagnosed AD patients at the very mild stage in the Clinical Dementia Rating scale 0.5 and mild stage Clinical Dementia Rating scale 1.0 in Taiwan and Japan. Psychometrics including the Ascertain Dementia 8 (AD8) questionnaire were administered to collect and compare the differences of the clinical presentation of the participants from the two countries.
Results
A total of 1189 participants, 641 from Taiwan and 548 from Japan, were recruited in the present study. In the very mild dementia group with Clinical Dementia Rating scale 0.5, apart from AD8‐2: reduced interest in hobbies/activities (P = 0.056) and AD8‐4: trouble learning how to use a tool, appliance or gadget (P = 0.224), other AD8 subitems were significantly different between the two countries. Japanese participants had a higher reported frequency of AD8‐5: forgetting the correct month or year (82.7%) than that (57.9%) in Taiwanese (P |
| doi_str_mv | 10.1111/ggi.12557 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1801424819</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1801424819</sourcerecordid><originalsourceid>FETCH-LOGICAL-i4777-1d93a90982f8e66874b0e0045057f2a052aac6e731992966ff5c5cf427c0fcd53</originalsourceid><addsrcrecordid>eNpdkMtOwzAQRS0EoqWw4AeQJRawSWs7fsTLqiqhqCoIFbG03MQpLnkRNyrh60kfdMFsZqQ5dzQ6AFxj1MdtDZZL28eEMXECuphS4SEm6eluph5mAe-AC-dWCGEhMT4HHcIJ5b4QXSDHukob6JqsXBeZg0UCh-nPh7GZqe4cjK0z2hloc_ikS51Dncdwru1G55fgLNGpM1eH3gNvD-P56NGbPoeT0XDqWSqE8HAsfS2RDEgSGM4DQRfIIEQZYiIhGjGidcSN8LGURHKeJCxiUUKJiFASxczvgfv93bIqvmrj1iqzLjJpqnNT1E7hAGFKaIBli97-Q1dFXeXtd1uqlYKwJC11c6DqRWZiVVY201Wj_qS0wGAPbGxqmuMeI7W1rVrbamdbheFkN7QJb5-wbm2-jwldfSoufMHU-yxUsymXjL68Kur_Au76fQU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1800590192</pqid></control><display><type>article</type><title>Early symptoms of Alzheimer's disease in Japan and Taiwan</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Yang, Yuan-Han ; Hsu, Chia-Ling ; Chou, Mei-Chuan ; Kasai, Mari ; Meguro, Kenichi ; Liu, Ching-Kuan</creator><creatorcontrib>Yang, Yuan-Han ; Hsu, Chia-Ling ; Chou, Mei-Chuan ; Kasai, Mari ; Meguro, Kenichi ; Liu, Ching-Kuan</creatorcontrib><description>Aim
The effects of Alzheimer's disease (AD) are making a major impact on the socioeconomic status of older adults in society. The recognition of early symptoms and clinical presentation are crucial issues to foster early diagnosis and treatment in order to have better therapeutic outcomes.
Methods
We recruited clinically diagnosed AD patients at the very mild stage in the Clinical Dementia Rating scale 0.5 and mild stage Clinical Dementia Rating scale 1.0 in Taiwan and Japan. Psychometrics including the Ascertain Dementia 8 (AD8) questionnaire were administered to collect and compare the differences of the clinical presentation of the participants from the two countries.
Results
A total of 1189 participants, 641 from Taiwan and 548 from Japan, were recruited in the present study. In the very mild dementia group with Clinical Dementia Rating scale 0.5, apart from AD8‐2: reduced interest in hobbies/activities (P = 0.056) and AD8‐4: trouble learning how to use a tool, appliance or gadget (P = 0.224), other AD8 subitems were significantly different between the two countries. Japanese participants had a higher reported frequency of AD8‐5: forgetting the correct month or year (82.7%) than that (57.9%) in Taiwanese (P < 0.001). Taiwanese participants had a higher reported frequency in AD8‐1: problems with judgment (20.3%), AD8‐3: repeats questions, stories or statements (67.5%), AD8‐6: difficulty handling complicated financial affairs (32.5%); AD8‐7: difficulty remembering appointments (53.8%); and AD8‐8: consistent problems with thinking and/or memory (89.3%) than those in Japanese participants.
Conclusion
Early symptoms of AD in both countries are different. The frequently reported early symptoms are important for primary physicians and the general population so that they can recognize the disease in the early stage so as to have a better therapeutic outcome. Such efforts would increase the awareness of dementia in the general population. Geriatr Gerontol Int 2016; 16: 797–803.</description><identifier>ISSN: 1444-1586</identifier><identifier>EISSN: 1447-0594</identifier><identifier>DOI: 10.1111/ggi.12557</identifier><identifier>PMID: 26246377</identifier><language>eng</language><publisher>Japan: Blackwell Publishing Ltd</publisher><subject>Aged ; Aged, 80 and over ; Alzheimer Disease - complications ; Alzheimer Disease - diagnosis ; Alzheimer Disease - psychology ; Alzheimer's disease ; Ascertain Dementia 8 ; Dementia ; Early Diagnosis ; Executive Function ; Female ; Humans ; Japan ; Male ; Neuropsychological Tests ; Psychometrics ; Surveys and Questionnaires ; Taiwan</subject><ispartof>Geriatrics & gerontology international, 2016-07, Vol.16 (7), p.797-803</ispartof><rights>2015 Japan Geriatrics Society</rights><rights>2015 Japan Geriatrics Society.</rights><rights>2016 Japan Geriatrics Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fggi.12557$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fggi.12557$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26246377$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Yuan-Han</creatorcontrib><creatorcontrib>Hsu, Chia-Ling</creatorcontrib><creatorcontrib>Chou, Mei-Chuan</creatorcontrib><creatorcontrib>Kasai, Mari</creatorcontrib><creatorcontrib>Meguro, Kenichi</creatorcontrib><creatorcontrib>Liu, Ching-Kuan</creatorcontrib><title>Early symptoms of Alzheimer's disease in Japan and Taiwan</title><title>Geriatrics & gerontology international</title><addtitle>Geriatr Gerontol Int</addtitle><description>Aim
The effects of Alzheimer's disease (AD) are making a major impact on the socioeconomic status of older adults in society. The recognition of early symptoms and clinical presentation are crucial issues to foster early diagnosis and treatment in order to have better therapeutic outcomes.
Methods
We recruited clinically diagnosed AD patients at the very mild stage in the Clinical Dementia Rating scale 0.5 and mild stage Clinical Dementia Rating scale 1.0 in Taiwan and Japan. Psychometrics including the Ascertain Dementia 8 (AD8) questionnaire were administered to collect and compare the differences of the clinical presentation of the participants from the two countries.
Results
A total of 1189 participants, 641 from Taiwan and 548 from Japan, were recruited in the present study. In the very mild dementia group with Clinical Dementia Rating scale 0.5, apart from AD8‐2: reduced interest in hobbies/activities (P = 0.056) and AD8‐4: trouble learning how to use a tool, appliance or gadget (P = 0.224), other AD8 subitems were significantly different between the two countries. Japanese participants had a higher reported frequency of AD8‐5: forgetting the correct month or year (82.7%) than that (57.9%) in Taiwanese (P < 0.001). Taiwanese participants had a higher reported frequency in AD8‐1: problems with judgment (20.3%), AD8‐3: repeats questions, stories or statements (67.5%), AD8‐6: difficulty handling complicated financial affairs (32.5%); AD8‐7: difficulty remembering appointments (53.8%); and AD8‐8: consistent problems with thinking and/or memory (89.3%) than those in Japanese participants.
Conclusion
Early symptoms of AD in both countries are different. The frequently reported early symptoms are important for primary physicians and the general population so that they can recognize the disease in the early stage so as to have a better therapeutic outcome. Such efforts would increase the awareness of dementia in the general population. Geriatr Gerontol Int 2016; 16: 797–803.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alzheimer Disease - complications</subject><subject>Alzheimer Disease - diagnosis</subject><subject>Alzheimer Disease - psychology</subject><subject>Alzheimer's disease</subject><subject>Ascertain Dementia 8</subject><subject>Dementia</subject><subject>Early Diagnosis</subject><subject>Executive Function</subject><subject>Female</subject><subject>Humans</subject><subject>Japan</subject><subject>Male</subject><subject>Neuropsychological Tests</subject><subject>Psychometrics</subject><subject>Surveys and Questionnaires</subject><subject>Taiwan</subject><issn>1444-1586</issn><issn>1447-0594</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkMtOwzAQRS0EoqWw4AeQJRawSWs7fsTLqiqhqCoIFbG03MQpLnkRNyrh60kfdMFsZqQ5dzQ6AFxj1MdtDZZL28eEMXECuphS4SEm6eluph5mAe-AC-dWCGEhMT4HHcIJ5b4QXSDHukob6JqsXBeZg0UCh-nPh7GZqe4cjK0z2hloc_ikS51Dncdwru1G55fgLNGpM1eH3gNvD-P56NGbPoeT0XDqWSqE8HAsfS2RDEgSGM4DQRfIIEQZYiIhGjGidcSN8LGURHKeJCxiUUKJiFASxczvgfv93bIqvmrj1iqzLjJpqnNT1E7hAGFKaIBli97-Q1dFXeXtd1uqlYKwJC11c6DqRWZiVVY201Wj_qS0wGAPbGxqmuMeI7W1rVrbamdbheFkN7QJb5-wbm2-jwldfSoufMHU-yxUsymXjL68Kur_Au76fQU</recordid><startdate>201607</startdate><enddate>201607</enddate><creator>Yang, Yuan-Han</creator><creator>Hsu, Chia-Ling</creator><creator>Chou, Mei-Chuan</creator><creator>Kasai, Mari</creator><creator>Meguro, Kenichi</creator><creator>Liu, Ching-Kuan</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201607</creationdate><title>Early symptoms of Alzheimer's disease in Japan and Taiwan</title><author>Yang, Yuan-Han ; Hsu, Chia-Ling ; Chou, Mei-Chuan ; Kasai, Mari ; Meguro, Kenichi ; Liu, Ching-Kuan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i4777-1d93a90982f8e66874b0e0045057f2a052aac6e731992966ff5c5cf427c0fcd53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alzheimer Disease - complications</topic><topic>Alzheimer Disease - diagnosis</topic><topic>Alzheimer Disease - psychology</topic><topic>Alzheimer's disease</topic><topic>Ascertain Dementia 8</topic><topic>Dementia</topic><topic>Early Diagnosis</topic><topic>Executive Function</topic><topic>Female</topic><topic>Humans</topic><topic>Japan</topic><topic>Male</topic><topic>Neuropsychological Tests</topic><topic>Psychometrics</topic><topic>Surveys and Questionnaires</topic><topic>Taiwan</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Yuan-Han</creatorcontrib><creatorcontrib>Hsu, Chia-Ling</creatorcontrib><creatorcontrib>Chou, Mei-Chuan</creatorcontrib><creatorcontrib>Kasai, Mari</creatorcontrib><creatorcontrib>Meguro, Kenichi</creatorcontrib><creatorcontrib>Liu, Ching-Kuan</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Geriatrics & gerontology international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Yuan-Han</au><au>Hsu, Chia-Ling</au><au>Chou, Mei-Chuan</au><au>Kasai, Mari</au><au>Meguro, Kenichi</au><au>Liu, Ching-Kuan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early symptoms of Alzheimer's disease in Japan and Taiwan</atitle><jtitle>Geriatrics & gerontology international</jtitle><addtitle>Geriatr Gerontol Int</addtitle><date>2016-07</date><risdate>2016</risdate><volume>16</volume><issue>7</issue><spage>797</spage><epage>803</epage><pages>797-803</pages><issn>1444-1586</issn><eissn>1447-0594</eissn><abstract>Aim
The effects of Alzheimer's disease (AD) are making a major impact on the socioeconomic status of older adults in society. The recognition of early symptoms and clinical presentation are crucial issues to foster early diagnosis and treatment in order to have better therapeutic outcomes.
Methods
We recruited clinically diagnosed AD patients at the very mild stage in the Clinical Dementia Rating scale 0.5 and mild stage Clinical Dementia Rating scale 1.0 in Taiwan and Japan. Psychometrics including the Ascertain Dementia 8 (AD8) questionnaire were administered to collect and compare the differences of the clinical presentation of the participants from the two countries.
Results
A total of 1189 participants, 641 from Taiwan and 548 from Japan, were recruited in the present study. In the very mild dementia group with Clinical Dementia Rating scale 0.5, apart from AD8‐2: reduced interest in hobbies/activities (P = 0.056) and AD8‐4: trouble learning how to use a tool, appliance or gadget (P = 0.224), other AD8 subitems were significantly different between the two countries. Japanese participants had a higher reported frequency of AD8‐5: forgetting the correct month or year (82.7%) than that (57.9%) in Taiwanese (P < 0.001). Taiwanese participants had a higher reported frequency in AD8‐1: problems with judgment (20.3%), AD8‐3: repeats questions, stories or statements (67.5%), AD8‐6: difficulty handling complicated financial affairs (32.5%); AD8‐7: difficulty remembering appointments (53.8%); and AD8‐8: consistent problems with thinking and/or memory (89.3%) than those in Japanese participants.
Conclusion
Early symptoms of AD in both countries are different. The frequently reported early symptoms are important for primary physicians and the general population so that they can recognize the disease in the early stage so as to have a better therapeutic outcome. Such efforts would increase the awareness of dementia in the general population. Geriatr Gerontol Int 2016; 16: 797–803.</abstract><cop>Japan</cop><pub>Blackwell Publishing Ltd</pub><pmid>26246377</pmid><doi>10.1111/ggi.12557</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1444-1586 |
| ispartof | Geriatrics & gerontology international, 2016-07, Vol.16 (7), p.797-803 |
| issn | 1444-1586 1447-0594 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1801424819 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aged Aged, 80 and over Alzheimer Disease - complications Alzheimer Disease - diagnosis Alzheimer Disease - psychology Alzheimer's disease Ascertain Dementia 8 Dementia Early Diagnosis Executive Function Female Humans Japan Male Neuropsychological Tests Psychometrics Surveys and Questionnaires Taiwan |
| title | Early symptoms of Alzheimer's disease in Japan and Taiwan |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T18%3A36%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Early%20symptoms%20of%20Alzheimer's%20disease%20in%20Japan%20and%20Taiwan&rft.jtitle=Geriatrics%20&%20gerontology%20international&rft.au=Yang,%20Yuan-Han&rft.date=2016-07&rft.volume=16&rft.issue=7&rft.spage=797&rft.epage=803&rft.pages=797-803&rft.issn=1444-1586&rft.eissn=1447-0594&rft_id=info:doi/10.1111/ggi.12557&rft_dat=%3Cproquest_pubme%3E1801424819%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1800590192&rft_id=info:pmid/26246377&rfr_iscdi=true |