The occurrence of 7- epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kaštela Bay)
Okadaic acid (OA) and 7- epi-pectenotoxin-2 seco acid (7- epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of Dinophysis acuta...
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Veröffentlicht in: | Toxicon (Oxford) 2001-06, Vol.39 (6), p.771-779 |
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creator | Pavela-Vrančič, M Meštrović, V Marasović, I Gillman, M Furey, A James, K.K |
description | Okadaic acid (OA) and 7-
epi-pectenotoxin-2 seco acid (7-
epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of
Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shellfish toxicity has been associated with the occurrence of the
Dinophysis species. This is the first report on the incidence of 7-
epi-PTX-2SA in the Adriatic region. |
doi_str_mv | 10.1016/S0041-0101(00)00203-8 |
format | Article |
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epi-pectenotoxin-2 seco acid (7-
epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of
Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shellfish toxicity has been associated with the occurrence of the
Dinophysis species. This is the first report on the incidence of 7-
epi-PTX-2SA in the Adriatic region.</description><identifier>ISSN: 0041-0101</identifier><identifier>EISSN: 1879-3150</identifier><identifier>DOI: 10.1016/S0041-0101(00)00203-8</identifier><identifier>PMID: 11137535</identifier><identifier>CODEN: TOXIA6</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>7- epi-Pectenotoxin-2 seco acid ; Adriatic Sea ; Animals ; Biological and medical sciences ; Chromatography, Liquid ; Diarrhetic Shellfish Poisoning ; Dinoflagellida - chemistry ; Dinophysis ; Dinophysis acuta ; epi-pectenotoxin-2 seco acid ; Foodborne Diseases ; Furans - chemistry ; Furans - metabolism ; Marine ; Marine Toxins - analysis ; Marine Toxins - toxicity ; Medical sciences ; Mice ; Mice, Inbred BALB C ; okadaic acid ; Okadaic Acid - analysis ; Okadaic Acid - toxicity ; pectenotoxin-2 ; Phytoplankton toxins ; Plant poisons toxicology ; Pyrans - chemistry ; Pyrans - metabolism ; Seawater ; Spectrometry, Fluorescence ; Toxicology</subject><ispartof>Toxicon (Oxford), 2001-06, Vol.39 (6), p.771-779</ispartof><rights>2001 Elsevier Science Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c486t-4e173663703d172aa94b48718023af891901a7a65e4c34d6b5e9a924c12358f53</citedby><cites>FETCH-LOGICAL-c486t-4e173663703d172aa94b48718023af891901a7a65e4c34d6b5e9a924c12358f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0041-0101(00)00203-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=871968$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11137535$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pavela-Vrančič, M</creatorcontrib><creatorcontrib>Meštrović, V</creatorcontrib><creatorcontrib>Marasović, I</creatorcontrib><creatorcontrib>Gillman, M</creatorcontrib><creatorcontrib>Furey, A</creatorcontrib><creatorcontrib>James, K.K</creatorcontrib><title>The occurrence of 7- epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kaštela Bay)</title><title>Toxicon (Oxford)</title><addtitle>Toxicon</addtitle><description>Okadaic acid (OA) and 7-
epi-pectenotoxin-2 seco acid (7-
epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of
Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shellfish toxicity has been associated with the occurrence of the
Dinophysis species. This is the first report on the incidence of 7-
epi-PTX-2SA in the Adriatic region.</description><subject>7- epi-Pectenotoxin-2 seco acid</subject><subject>Adriatic Sea</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Chromatography, Liquid</subject><subject>Diarrhetic Shellfish Poisoning</subject><subject>Dinoflagellida - chemistry</subject><subject>Dinophysis</subject><subject>Dinophysis acuta</subject><subject>epi-pectenotoxin-2 seco acid</subject><subject>Foodborne Diseases</subject><subject>Furans - chemistry</subject><subject>Furans - metabolism</subject><subject>Marine</subject><subject>Marine Toxins - analysis</subject><subject>Marine Toxins - toxicity</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>okadaic acid</subject><subject>Okadaic Acid - analysis</subject><subject>Okadaic Acid - toxicity</subject><subject>pectenotoxin-2</subject><subject>Phytoplankton toxins</subject><subject>Plant poisons toxicology</subject><subject>Pyrans - chemistry</subject><subject>Pyrans - metabolism</subject><subject>Seawater</subject><subject>Spectrometry, Fluorescence</subject><subject>Toxicology</subject><issn>0041-0101</issn><issn>1879-3150</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc9u1DAQhy0EotuFRwBZQkLtwTCOk9g5VW3Fn6qVOFDO1qwzEUbZeLG9lD5OH4b3wtldlSMnj0bfb8b-zNgrCe8kyPb9V4BaCij1CcApQAVKmCdsIY3uhJINPGWLR-SIHaf0AwCU6drn7EhKqXSjmgWbbr8TD85tY6TJlXLgWnDaeLEhl2kKOfz2k6h4Ihc4Ot9zP_FcQi5gyjjyO8wU0xzcdWnKsXTP--gxe8dPrvHPQ6YR-QXen75gzwYcE708nEv27eOH28vP4ubLp6vL8xvhatNmUZPUqm2VBtVLXSF29ao2WhqoFA6mkx1I1Ng2VDtV9-2qoQ67qnayUo0ZGrVkb_dzNzH83FLKdu2To3HEicI22TJJgi4blqzZgy6GlCINdhP9GuO9lWBn0XYn2s4WLYDdibam5F4fFmxXa-r_pQ5mC_DmAGByOA4RJ-fTI1ce07XzmLM9RUXGL0_RJufnj-h9LP5tH_x_LvIXdeaXgw</recordid><startdate>20010601</startdate><enddate>20010601</enddate><creator>Pavela-Vrančič, M</creator><creator>Meštrović, V</creator><creator>Marasović, I</creator><creator>Gillman, M</creator><creator>Furey, A</creator><creator>James, K.K</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TN</scope><scope>7TV</scope><scope>7U7</scope><scope>C1K</scope><scope>F1W</scope><scope>H95</scope><scope>H97</scope><scope>L.G</scope><scope>M7N</scope></search><sort><creationdate>20010601</creationdate><title>The occurrence of 7- epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kaštela Bay)</title><author>Pavela-Vrančič, M ; 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epi-pectenotoxin-2 seco acid (7-
epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of
Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shellfish toxicity has been associated with the occurrence of the
Dinophysis species. This is the first report on the incidence of 7-
epi-PTX-2SA in the Adriatic region.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>11137535</pmid><doi>10.1016/S0041-0101(00)00203-8</doi><tpages>9</tpages></addata></record> |
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subjects | 7- epi-Pectenotoxin-2 seco acid Adriatic Sea Animals Biological and medical sciences Chromatography, Liquid Diarrhetic Shellfish Poisoning Dinoflagellida - chemistry Dinophysis Dinophysis acuta epi-pectenotoxin-2 seco acid Foodborne Diseases Furans - chemistry Furans - metabolism Marine Marine Toxins - analysis Marine Toxins - toxicity Medical sciences Mice Mice, Inbred BALB C okadaic acid Okadaic Acid - analysis Okadaic Acid - toxicity pectenotoxin-2 Phytoplankton toxins Plant poisons toxicology Pyrans - chemistry Pyrans - metabolism Seawater Spectrometry, Fluorescence Toxicology |
title | The occurrence of 7- epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kaštela Bay) |
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