The occurrence of 7- epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kaštela Bay)

Okadaic acid (OA) and 7- epi-pectenotoxin-2 seco acid (7- epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of Dinophysis acuta...

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Veröffentlicht in:Toxicon (Oxford) 2001-06, Vol.39 (6), p.771-779
Hauptverfasser: Pavela-Vrančič, M, Meštrović, V, Marasović, I, Gillman, M, Furey, A, James, K.K
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container_title Toxicon (Oxford)
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creator Pavela-Vrančič, M
Meštrović, V
Marasović, I
Gillman, M
Furey, A
James, K.K
description Okadaic acid (OA) and 7- epi-pectenotoxin-2 seco acid (7- epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shellfish toxicity has been associated with the occurrence of the Dinophysis species. This is the first report on the incidence of 7- epi-PTX-2SA in the Adriatic region.
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subjects 7- epi-Pectenotoxin-2 seco acid
Adriatic Sea
Animals
Biological and medical sciences
Chromatography, Liquid
Diarrhetic Shellfish Poisoning
Dinoflagellida - chemistry
Dinophysis
Dinophysis acuta
epi-pectenotoxin-2 seco acid
Foodborne Diseases
Furans - chemistry
Furans - metabolism
Marine
Marine Toxins - analysis
Marine Toxins - toxicity
Medical sciences
Mice
Mice, Inbred BALB C
okadaic acid
Okadaic Acid - analysis
Okadaic Acid - toxicity
pectenotoxin-2
Phytoplankton toxins
Plant poisons toxicology
Pyrans - chemistry
Pyrans - metabolism
Seawater
Spectrometry, Fluorescence
Toxicology
title The occurrence of 7- epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kaštela Bay)
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