Metal free TBHP-promoted intramolecular carbonylation of arenes via radical cross-dehydrogenative coupling: synthesis of indenoquinolinones, 4-azafluorenones and fluorenones

Metal free TBHP-promoted intramolecular carbonylation of arenes via radical cross-dehydrogenative coupling: synthesis of indenoquinolinones, 4-azafluorenones and fluorenones

A metal-free, TBHP-promoted economical route is developed via the sp(2) C-H bond functionalization strategy for the synthesis of indenoquinolinones, 4-azafluorenones and fluorenones. Reactions provided excellent yield of the products under mild conditions. We have successfully synthesized 11H-indeno...

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Veröffentlicht in:Organic & biomolecular chemistry 2016-01, Vol.14 (26), p.6328-6336
Hauptverfasser: Mishra, Kalpana, Pandey, Ashok Kumar, Singh, Jay Bahadur, Singh, Radhey M
Format: Artikel
Sprache:eng
Schlagworte:
Aza Compounds - chemical synthesis
Aza Compounds - chemistry
Calixarenes - chemistry
Fluorenes - chemical synthesis
Fluorenes - chemistry
Hydrogenation
Molecular Structure
tert-Butylhydroperoxide - chemistry
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container_end_page 6336
container_issue 26
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container_title Organic & biomolecular chemistry
container_volume 14
creator Mishra, Kalpana
Pandey, Ashok Kumar
Singh, Jay Bahadur
Singh, Radhey M
description A metal-free, TBHP-promoted economical route is developed via the sp(2) C-H bond functionalization strategy for the synthesis of indenoquinolinones, 4-azafluorenones and fluorenones. Reactions provided excellent yield of the products under mild conditions. We have successfully synthesized 11H-indeno[1,2-b]quinolin-11-one, an antibacterial agent, in excellent yields.
doi_str_mv 10.1039/c6ob00998k
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source MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection
subjects Aza Compounds - chemical synthesis
Aza Compounds - chemistry
Calixarenes - chemistry
Fluorenes - chemical synthesis
Fluorenes - chemistry
Hydrogenation
Molecular Structure
tert-Butylhydroperoxide - chemistry
title Metal free TBHP-promoted intramolecular carbonylation of arenes via radical cross-dehydrogenative coupling: synthesis of indenoquinolinones, 4-azafluorenones and fluorenones
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