Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal

[Display omitted] •Free fatty acids binding amplify the reactivity of HSA Cys34 thiol group.•HSA free thiol group reaction kinetic changes with different fatty acids.•Fatty acids increase HSA thiol group carbonylation with methylglyoxal.•Reactivity of thiol group of carbonylated HSA depends on type...

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Veröffentlicht in:	Chemico-biological interactions 2014-12, Vol.224, p.42-50
Hauptverfasser:	Pavićević, Ivan D., Jovanović, Vesna B., Takić, Marija M., Penezić, Ana Z., Aćimović, Jelena M., Mandić, Ljuba M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumin Cysteine - analysis Cysteine - chemistry Fatty Acids - chemistry Fatty acids binding Fish Oils - metabolism Free Radical Scavengers - chemistry Glycosylation Humans Kinetics Methylglyoxal Protein Binding Protein carbonylation Pyruvaldehyde - chemistry Serum Albumin - chemistry Thiol group reactivity
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