Changes in cellular thiol content and intracellular Zn(2+) level by 1,4-naphthoquinone in rat thymocytes

1,4-Naphthoquinone is an active metabolite of naphthalene and it is also found in diesel exhaust particles. It is known to cause oxidative stress. In this study, we characterized 1,4-naphthoquinone-mediated cytotoxicity and its effects on the levels of non-protein thiols and intracellular Zn(2+) in...

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Veröffentlicht in:	Chemico-biological interactions 2014-10, Vol.222, p.1-6
Hauptverfasser:	Fukunaga, Eri, Ishida, Shiro, Oyama, Yasuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Survival - drug effects Fluoresceins Fluorescent Dyes Naphthoquinones - toxicity Oxidative Stress - drug effects Polycyclic Compounds Rats Rats, Wistar Sulfhydryl Compounds - metabolism Thymocytes - drug effects Thymocytes - metabolism Thymocytes - pathology Zinc - metabolism
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