One-step synthesis of redox-active polymer/AU nanocomposites for electrochemical immunoassay of multiplexed tumor markers

In this work, a simple and sensitive multiplexed immunoassay protocol for simultaneous electrochemical determination of alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) was designed using redox-active nanocomposites. As the redox-active species, the poly(o-phenylenediamine) (POPD)/Au nanoc...

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Veröffentlicht in:	Biosensors & bioelectronics 2015-03, Vol.65, p.307-313
Hauptverfasser:	Liu, Zhimin, Rong, Qinfeng, Ma, Zhanfang, Han, Hongliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-fetoprotein alpha-Fetoproteins - analysis Aniline Compounds - chemical synthesis Aniline Compounds - chemistry Antigens Biosensing Techniques - methods Biosensors Carcinoembryonic antigen Carcinoembryonic Antigen - blood Electrochemical immunosensor Electrochemical Techniques - methods ELISA Ferrous Compounds - chemical synthesis Ferrous Compounds - chemistry Gold Gold - chemistry Humans Immunoassay Immunoassay - methods Limit of Detection Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Multiplexing Nanocomposites Nanocomposites - chemistry Nanocomposites - ultrastructure Oxidants Oxidation-Reduction Phenylenediamines - chemical synthesis Phenylenediamines - chemistry Poly(o-phenylenediamine)/Au nanocomposite Poly(vinyl ferrocene-2-aminothiophenol)/Au nanocomposite Polyvinyls - chemical synthesis Polyvinyls - chemistry
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