Implementation of the ‘Sapere Migliora’ information aid for newly diagnosed people with multiple sclerosis in routine clinical practice: a late-phase controlled trial
Background: The SIMS-Trial showed that the ‘Sapere Migliora’ information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction with care. Objectives: The objectives of this paper are to assess the effectiveness of the IA in clinica...
Gespeichert in:
| Veröffentlicht in: | Multiple sclerosis 2014-08, Vol.20 (9), p.1234-1243 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1243 |
|---|---|
| container_issue | 9 |
| container_start_page | 1234 |
| container_title | Multiple sclerosis |
| container_volume | 20 |
| creator | Giordano, A Lugaresi, A Confalonieri, P Granella, F Radice, D Trojano, M Martinelli, V Solari, A Giordano, A Martinelli, V Lugaresi, A Pucci, E Granella, F Trojano, M Solari, A Messmer Uccelli, M Ferrari, G Martini, F Radice, D D’Annunzio, G Farina, D Travaglini, D Pietrolongo, E Onofrj, M Torri Clerici, V Bonanno, S Brambilla, L Confalonieri, P Radaelli, M Messina, J Comi, G Tortorella, C Luciannatelli, E Senesi, C Tsantes, E Conti, MZ Rottoli, MR Bellantonio, P Fischetti, M Fantozzi, R Pala, A Traccis, S Di Battista, G Bianchi, M Benedetti, MD Gaetani, L Di Filippo, M Carolei, A Totaro, R Lanzillo, R Brescia Morra, V Coppola, R Cottone, S Chiavazza, C Cavalla, P Leonardi, C Aguglia, U Ziuliani, C Valla, P Sasanelli, F Valentino, P Quattrone, A Martino, Policlinico G. Russo, M Vita, G Immovilli, P |
| description | Background:
The SIMS-Trial showed that the ‘Sapere Migliora’ information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction with care.
Objectives:
The objectives of this paper are to assess the effectiveness of the IA in clinical practice and to compare the whole IA with the take-home booklet/website component alone.
Methods:
After updating the IA and replacing the CD with a website, a prospective, open-label non-randomised controlled trial compared the whole IA (group A, five SIMS-Trial centres) to take-home (group B, 16 centres). One month after the intervention, participants completed the MS Knowledge Questionnaire (MSKQ), care satisfaction questionnaire (COSM-R) (primary study outcomes), Hospital and Anxiety Depression Scale, and ad hoc questionnaire appraising the IA.
Results:
We enrolled 159 newly diagnosed PwMS (May 2012–March 2013). Drop-outs were four of 77 (5%, group A) and 11/82 (13%, group B). Primary endpoint (highest tertile both for MSKQ and COSM-R section 2 scores) was achieved by 38/77 (49%) group A and 33/82 (40%) group B (p = 0.25). Attainment of secondary outcomes was also similar between groups.
Conclusions:
This study shows that the entire IA is not superior to the booklet/website alone, and that both are comparable in efficacy to the intervention arm of the SIMS-Trial.
Trial registration number:
ISRCTN78940214. |
| doi_str_mv | 10.1177/1352458513519180 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1800701603</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1352458513519180</sage_id><sourcerecordid>3368934701</sourcerecordid><originalsourceid>FETCH-LOGICAL-c428t-2601b3669fd8e3f4b8986149e53789546c26f7dcd667b2512647ce3d3d74fdd3</originalsourceid><addsrcrecordid>eNqFkc9uFSEUxifGxtbq3pUhMSZuxsLAAOPONP5p0qYLu59w4XAvDQMjMGm662PoK_hYfRK5udc_aWJcHU7O73zA9zXNC4LfEiLECaF9x3rZ10oGIvGj5ogwIVo8CPy4nuu43c4Pm6c5X2OMhaD9k-awY6wjFPdHzY-zafYwQSiquBhQtKhsAN3fffuiZkiALtzau5jU_d135IKNadqByhlUOxTgxt8i49Q6xAwGzRCrILpxZYOmxRe37bL2kGJ2uUqgFJfiAiDtXXBaeTQnpYvT8A4p5FWBdt6oXOcxlBS9r6IlOeWfNQdW-QzP9_W4ufr44er0c3t--ens9P15q1knS9txTFaU88EaCdSylRwkJ2yAngo59IzrjlthtOFcrLqedJwJDdRQI5g1hh43b3ayc4pfF8hlnFzW4L0KEJc8VpuxwIRj-n-US1qT4XSLvnqAXsclhfqPkfSMUcEl7yqFd5SubuUEdpyTm1S6HQket4mPDxOvKy_3wstqAvN74VfEFXi9B1Subtukgnb5Dyc5HqoLlWt3XFZr-Ot1_7r4J8PTw0Y</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1544376862</pqid></control><display><type>article</type><title>Implementation of the ‘Sapere Migliora’ information aid for newly diagnosed people with multiple sclerosis in routine clinical practice: a late-phase controlled trial</title><source>MEDLINE</source><source>SAGE Complete</source><creator>Giordano, A ; Lugaresi, A ; Confalonieri, P ; Granella, F ; Radice, D ; Trojano, M ; Martinelli, V ; Solari, A ; Giordano, A ; Martinelli, V ; Lugaresi, A ; Pucci, E ; Granella, F ; Trojano, M ; Solari, A ; Messmer Uccelli, M ; Ferrari, G ; Martini, F ; Radice, D ; D’Annunzio, G ; Farina, D ; Travaglini, D ; Pietrolongo, E ; Onofrj, M ; Torri Clerici, V ; Bonanno, S ; Brambilla, L ; Confalonieri, P ; Radaelli, M ; Messina, J ; Comi, G ; Tortorella, C ; Luciannatelli, E ; Senesi, C ; Tsantes, E ; Conti, MZ ; Rottoli, MR ; Bellantonio, P ; Fischetti, M ; Fantozzi, R ; Pala, A ; Traccis, S ; Di Battista, G ; Bianchi, M ; Benedetti, MD ; Gaetani, L ; Di Filippo, M ; Carolei, A ; Totaro, R ; Lanzillo, R ; Brescia Morra, V ; Coppola, R ; Cottone, S ; Chiavazza, C ; Cavalla, P ; Leonardi, C ; Aguglia, U ; Ziuliani, C ; Valla, P ; Sasanelli, F ; Valentino, P ; Quattrone, A ; Martino, Policlinico G. ; Russo, M ; Vita, G ; Immovilli, P</creator><creatorcontrib>Giordano, A ; Lugaresi, A ; Confalonieri, P ; Granella, F ; Radice, D ; Trojano, M ; Martinelli, V ; Solari, A ; Giordano, A ; Martinelli, V ; Lugaresi, A ; Pucci, E ; Granella, F ; Trojano, M ; Solari, A ; Messmer Uccelli, M ; Ferrari, G ; Martini, F ; Radice, D ; D’Annunzio, G ; Farina, D ; Travaglini, D ; Pietrolongo, E ; Onofrj, M ; Torri Clerici, V ; Bonanno, S ; Brambilla, L ; Confalonieri, P ; Radaelli, M ; Messina, J ; Comi, G ; Tortorella, C ; Luciannatelli, E ; Senesi, C ; Tsantes, E ; Conti, MZ ; Rottoli, MR ; Bellantonio, P ; Fischetti, M ; Fantozzi, R ; Pala, A ; Traccis, S ; Di Battista, G ; Bianchi, M ; Benedetti, MD ; Gaetani, L ; Di Filippo, M ; Carolei, A ; Totaro, R ; Lanzillo, R ; Brescia Morra, V ; Coppola, R ; Cottone, S ; Chiavazza, C ; Cavalla, P ; Leonardi, C ; Aguglia, U ; Ziuliani, C ; Valla, P ; Sasanelli, F ; Valentino, P ; Quattrone, A ; Martino, Policlinico G. ; Russo, M ; Vita, G ; Immovilli, P ; SIMS-Practice group ; on behalf of the SIMS-Practice group</creatorcontrib><description>Background:
The SIMS-Trial showed that the ‘Sapere Migliora’ information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction with care.
Objectives:
The objectives of this paper are to assess the effectiveness of the IA in clinical practice and to compare the whole IA with the take-home booklet/website component alone.
Methods:
After updating the IA and replacing the CD with a website, a prospective, open-label non-randomised controlled trial compared the whole IA (group A, five SIMS-Trial centres) to take-home (group B, 16 centres). One month after the intervention, participants completed the MS Knowledge Questionnaire (MSKQ), care satisfaction questionnaire (COSM-R) (primary study outcomes), Hospital and Anxiety Depression Scale, and ad hoc questionnaire appraising the IA.
Results:
We enrolled 159 newly diagnosed PwMS (May 2012–March 2013). Drop-outs were four of 77 (5%, group A) and 11/82 (13%, group B). Primary endpoint (highest tertile both for MSKQ and COSM-R section 2 scores) was achieved by 38/77 (49%) group A and 33/82 (40%) group B (p = 0.25). Attainment of secondary outcomes was also similar between groups.
Conclusions:
This study shows that the entire IA is not superior to the booklet/website alone, and that both are comparable in efficacy to the intervention arm of the SIMS-Trial.
Trial registration number:
ISRCTN78940214.</description><identifier>ISSN: 1352-4585</identifier><identifier>EISSN: 1477-0970</identifier><identifier>DOI: 10.1177/1352458513519180</identifier><identifier>PMID: 24421305</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Comprehension ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Female ; Health Knowledge, Attitudes, Practice ; Health Literacy ; Humans ; Immunomodulators ; Internet ; Interviews as Topic ; Italy ; Male ; Medical sciences ; Middle Aged ; Multiple Sclerosis - diagnosis ; Multiple Sclerosis - physiopathology ; Multiple Sclerosis - psychology ; Multiple Sclerosis - therapy ; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis ; Neurology ; Patient Education as Topic - methods ; Patient Satisfaction ; Pharmacology. Drug treatments ; Prospective Studies ; Surveys and Questionnaires ; Treatment Outcome ; Young Adult</subject><ispartof>Multiple sclerosis, 2014-08, Vol.20 (9), p.1234-1243</ispartof><rights>The Author(s) 2014</rights><rights>2015 INIST-CNRS</rights><rights>The Author(s) 2014.</rights><rights>SAGE Publications © Aug 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c428t-2601b3669fd8e3f4b8986149e53789546c26f7dcd667b2512647ce3d3d74fdd3</citedby><cites>FETCH-LOGICAL-c428t-2601b3669fd8e3f4b8986149e53789546c26f7dcd667b2512647ce3d3d74fdd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1352458513519180$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1352458513519180$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28609512$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24421305$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Giordano, A</creatorcontrib><creatorcontrib>Lugaresi, A</creatorcontrib><creatorcontrib>Confalonieri, P</creatorcontrib><creatorcontrib>Granella, F</creatorcontrib><creatorcontrib>Radice, D</creatorcontrib><creatorcontrib>Trojano, M</creatorcontrib><creatorcontrib>Martinelli, V</creatorcontrib><creatorcontrib>Solari, A</creatorcontrib><creatorcontrib>Giordano, A</creatorcontrib><creatorcontrib>Martinelli, V</creatorcontrib><creatorcontrib>Lugaresi, A</creatorcontrib><creatorcontrib>Pucci, E</creatorcontrib><creatorcontrib>Granella, F</creatorcontrib><creatorcontrib>Trojano, M</creatorcontrib><creatorcontrib>Solari, A</creatorcontrib><creatorcontrib>Messmer Uccelli, M</creatorcontrib><creatorcontrib>Ferrari, G</creatorcontrib><creatorcontrib>Martini, F</creatorcontrib><creatorcontrib>Radice, D</creatorcontrib><creatorcontrib>D’Annunzio, G</creatorcontrib><creatorcontrib>Farina, D</creatorcontrib><creatorcontrib>Travaglini, D</creatorcontrib><creatorcontrib>Pietrolongo, E</creatorcontrib><creatorcontrib>Onofrj, M</creatorcontrib><creatorcontrib>Torri Clerici, V</creatorcontrib><creatorcontrib>Bonanno, S</creatorcontrib><creatorcontrib>Brambilla, L</creatorcontrib><creatorcontrib>Confalonieri, P</creatorcontrib><creatorcontrib>Radaelli, M</creatorcontrib><creatorcontrib>Messina, J</creatorcontrib><creatorcontrib>Comi, G</creatorcontrib><creatorcontrib>Tortorella, C</creatorcontrib><creatorcontrib>Luciannatelli, E</creatorcontrib><creatorcontrib>Senesi, C</creatorcontrib><creatorcontrib>Tsantes, E</creatorcontrib><creatorcontrib>Conti, MZ</creatorcontrib><creatorcontrib>Rottoli, MR</creatorcontrib><creatorcontrib>Bellantonio, P</creatorcontrib><creatorcontrib>Fischetti, M</creatorcontrib><creatorcontrib>Fantozzi, R</creatorcontrib><creatorcontrib>Pala, A</creatorcontrib><creatorcontrib>Traccis, S</creatorcontrib><creatorcontrib>Di Battista, G</creatorcontrib><creatorcontrib>Bianchi, M</creatorcontrib><creatorcontrib>Benedetti, MD</creatorcontrib><creatorcontrib>Gaetani, L</creatorcontrib><creatorcontrib>Di Filippo, M</creatorcontrib><creatorcontrib>Carolei, A</creatorcontrib><creatorcontrib>Totaro, R</creatorcontrib><creatorcontrib>Lanzillo, R</creatorcontrib><creatorcontrib>Brescia Morra, V</creatorcontrib><creatorcontrib>Coppola, R</creatorcontrib><creatorcontrib>Cottone, S</creatorcontrib><creatorcontrib>Chiavazza, C</creatorcontrib><creatorcontrib>Cavalla, P</creatorcontrib><creatorcontrib>Leonardi, C</creatorcontrib><creatorcontrib>Aguglia, U</creatorcontrib><creatorcontrib>Ziuliani, C</creatorcontrib><creatorcontrib>Valla, P</creatorcontrib><creatorcontrib>Sasanelli, F</creatorcontrib><creatorcontrib>Valentino, P</creatorcontrib><creatorcontrib>Quattrone, A</creatorcontrib><creatorcontrib>Martino, Policlinico G.</creatorcontrib><creatorcontrib>Russo, M</creatorcontrib><creatorcontrib>Vita, G</creatorcontrib><creatorcontrib>Immovilli, P</creatorcontrib><creatorcontrib>SIMS-Practice group</creatorcontrib><creatorcontrib>on behalf of the SIMS-Practice group</creatorcontrib><title>Implementation of the ‘Sapere Migliora’ information aid for newly diagnosed people with multiple sclerosis in routine clinical practice: a late-phase controlled trial</title><title>Multiple sclerosis</title><addtitle>Mult Scler</addtitle><description>Background:
The SIMS-Trial showed that the ‘Sapere Migliora’ information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction with care.
Objectives:
The objectives of this paper are to assess the effectiveness of the IA in clinical practice and to compare the whole IA with the take-home booklet/website component alone.
Methods:
After updating the IA and replacing the CD with a website, a prospective, open-label non-randomised controlled trial compared the whole IA (group A, five SIMS-Trial centres) to take-home (group B, 16 centres). One month after the intervention, participants completed the MS Knowledge Questionnaire (MSKQ), care satisfaction questionnaire (COSM-R) (primary study outcomes), Hospital and Anxiety Depression Scale, and ad hoc questionnaire appraising the IA.
Results:
We enrolled 159 newly diagnosed PwMS (May 2012–March 2013). Drop-outs were four of 77 (5%, group A) and 11/82 (13%, group B). Primary endpoint (highest tertile both for MSKQ and COSM-R section 2 scores) was achieved by 38/77 (49%) group A and 33/82 (40%) group B (p = 0.25). Attainment of secondary outcomes was also similar between groups.
Conclusions:
This study shows that the entire IA is not superior to the booklet/website alone, and that both are comparable in efficacy to the intervention arm of the SIMS-Trial.
Trial registration number:
ISRCTN78940214.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Comprehension</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Female</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>Health Literacy</subject><subject>Humans</subject><subject>Immunomodulators</subject><subject>Internet</subject><subject>Interviews as Topic</subject><subject>Italy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multiple Sclerosis - diagnosis</subject><subject>Multiple Sclerosis - physiopathology</subject><subject>Multiple Sclerosis - psychology</subject><subject>Multiple Sclerosis - therapy</subject><subject>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</subject><subject>Neurology</subject><subject>Patient Education as Topic - methods</subject><subject>Patient Satisfaction</subject><subject>Pharmacology. Drug treatments</subject><subject>Prospective Studies</subject><subject>Surveys and Questionnaires</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>1352-4585</issn><issn>1477-0970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkc9uFSEUxifGxtbq3pUhMSZuxsLAAOPONP5p0qYLu59w4XAvDQMjMGm662PoK_hYfRK5udc_aWJcHU7O73zA9zXNC4LfEiLECaF9x3rZ10oGIvGj5ogwIVo8CPy4nuu43c4Pm6c5X2OMhaD9k-awY6wjFPdHzY-zafYwQSiquBhQtKhsAN3fffuiZkiALtzau5jU_d135IKNadqByhlUOxTgxt8i49Q6xAwGzRCrILpxZYOmxRe37bL2kGJ2uUqgFJfiAiDtXXBaeTQnpYvT8A4p5FWBdt6oXOcxlBS9r6IlOeWfNQdW-QzP9_W4ufr44er0c3t--ens9P15q1knS9txTFaU88EaCdSylRwkJ2yAngo59IzrjlthtOFcrLqedJwJDdRQI5g1hh43b3ayc4pfF8hlnFzW4L0KEJc8VpuxwIRj-n-US1qT4XSLvnqAXsclhfqPkfSMUcEl7yqFd5SubuUEdpyTm1S6HQket4mPDxOvKy_3wstqAvN74VfEFXi9B1Subtukgnb5Dyc5HqoLlWt3XFZr-Ot1_7r4J8PTw0Y</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Giordano, A</creator><creator>Lugaresi, A</creator><creator>Confalonieri, P</creator><creator>Granella, F</creator><creator>Radice, D</creator><creator>Trojano, M</creator><creator>Martinelli, V</creator><creator>Solari, A</creator><creator>Giordano, A</creator><creator>Martinelli, V</creator><creator>Lugaresi, A</creator><creator>Pucci, E</creator><creator>Granella, F</creator><creator>Trojano, M</creator><creator>Solari, A</creator><creator>Messmer Uccelli, M</creator><creator>Ferrari, G</creator><creator>Martini, F</creator><creator>Radice, D</creator><creator>D’Annunzio, G</creator><creator>Farina, D</creator><creator>Travaglini, D</creator><creator>Pietrolongo, E</creator><creator>Onofrj, M</creator><creator>Torri Clerici, V</creator><creator>Bonanno, S</creator><creator>Brambilla, L</creator><creator>Confalonieri, P</creator><creator>Radaelli, M</creator><creator>Messina, J</creator><creator>Comi, G</creator><creator>Tortorella, C</creator><creator>Luciannatelli, E</creator><creator>Senesi, C</creator><creator>Tsantes, E</creator><creator>Conti, MZ</creator><creator>Rottoli, MR</creator><creator>Bellantonio, P</creator><creator>Fischetti, M</creator><creator>Fantozzi, R</creator><creator>Pala, A</creator><creator>Traccis, S</creator><creator>Di Battista, G</creator><creator>Bianchi, M</creator><creator>Benedetti, MD</creator><creator>Gaetani, L</creator><creator>Di Filippo, M</creator><creator>Carolei, A</creator><creator>Totaro, R</creator><creator>Lanzillo, R</creator><creator>Brescia Morra, V</creator><creator>Coppola, R</creator><creator>Cottone, S</creator><creator>Chiavazza, C</creator><creator>Cavalla, P</creator><creator>Leonardi, C</creator><creator>Aguglia, U</creator><creator>Ziuliani, C</creator><creator>Valla, P</creator><creator>Sasanelli, F</creator><creator>Valentino, P</creator><creator>Quattrone, A</creator><creator>Martino, Policlinico G.</creator><creator>Russo, M</creator><creator>Vita, G</creator><creator>Immovilli, P</creator><general>SAGE Publications</general><general>Sage Publications</general><general>Sage Publications Ltd</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20140801</creationdate><title>Implementation of the ‘Sapere Migliora’ information aid for newly diagnosed people with multiple sclerosis in routine clinical practice: a late-phase controlled trial</title><author>Giordano, A ; Lugaresi, A ; Confalonieri, P ; Granella, F ; Radice, D ; Trojano, M ; Martinelli, V ; Solari, A ; Giordano, A ; Martinelli, V ; Lugaresi, A ; Pucci, E ; Granella, F ; Trojano, M ; Solari, A ; Messmer Uccelli, M ; Ferrari, G ; Martini, F ; Radice, D ; D’Annunzio, G ; Farina, D ; Travaglini, D ; Pietrolongo, E ; Onofrj, M ; Torri Clerici, V ; Bonanno, S ; Brambilla, L ; Confalonieri, P ; Radaelli, M ; Messina, J ; Comi, G ; Tortorella, C ; Luciannatelli, E ; Senesi, C ; Tsantes, E ; Conti, MZ ; Rottoli, MR ; Bellantonio, P ; Fischetti, M ; Fantozzi, R ; Pala, A ; Traccis, S ; Di Battista, G ; Bianchi, M ; Benedetti, MD ; Gaetani, L ; Di Filippo, M ; Carolei, A ; Totaro, R ; Lanzillo, R ; Brescia Morra, V ; Coppola, R ; Cottone, S ; Chiavazza, C ; Cavalla, P ; Leonardi, C ; Aguglia, U ; Ziuliani, C ; Valla, P ; Sasanelli, F ; Valentino, P ; Quattrone, A ; Martino, Policlinico G. ; Russo, M ; Vita, G ; Immovilli, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-2601b3669fd8e3f4b8986149e53789546c26f7dcd667b2512647ce3d3d74fdd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Comprehension</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Female</topic><topic>Health Knowledge, Attitudes, Practice</topic><topic>Health Literacy</topic><topic>Humans</topic><topic>Immunomodulators</topic><topic>Internet</topic><topic>Interviews as Topic</topic><topic>Italy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multiple Sclerosis - diagnosis</topic><topic>Multiple Sclerosis - physiopathology</topic><topic>Multiple Sclerosis - psychology</topic><topic>Multiple Sclerosis - therapy</topic><topic>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</topic><topic>Neurology</topic><topic>Patient Education as Topic - methods</topic><topic>Patient Satisfaction</topic><topic>Pharmacology. Drug treatments</topic><topic>Prospective Studies</topic><topic>Surveys and Questionnaires</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Giordano, A</creatorcontrib><creatorcontrib>Lugaresi, A</creatorcontrib><creatorcontrib>Confalonieri, P</creatorcontrib><creatorcontrib>Granella, F</creatorcontrib><creatorcontrib>Radice, D</creatorcontrib><creatorcontrib>Trojano, M</creatorcontrib><creatorcontrib>Martinelli, V</creatorcontrib><creatorcontrib>Solari, A</creatorcontrib><creatorcontrib>Giordano, A</creatorcontrib><creatorcontrib>Martinelli, V</creatorcontrib><creatorcontrib>Lugaresi, A</creatorcontrib><creatorcontrib>Pucci, E</creatorcontrib><creatorcontrib>Granella, F</creatorcontrib><creatorcontrib>Trojano, M</creatorcontrib><creatorcontrib>Solari, A</creatorcontrib><creatorcontrib>Messmer Uccelli, M</creatorcontrib><creatorcontrib>Ferrari, G</creatorcontrib><creatorcontrib>Martini, F</creatorcontrib><creatorcontrib>Radice, D</creatorcontrib><creatorcontrib>D’Annunzio, G</creatorcontrib><creatorcontrib>Farina, D</creatorcontrib><creatorcontrib>Travaglini, D</creatorcontrib><creatorcontrib>Pietrolongo, E</creatorcontrib><creatorcontrib>Onofrj, M</creatorcontrib><creatorcontrib>Torri Clerici, V</creatorcontrib><creatorcontrib>Bonanno, S</creatorcontrib><creatorcontrib>Brambilla, L</creatorcontrib><creatorcontrib>Confalonieri, P</creatorcontrib><creatorcontrib>Radaelli, M</creatorcontrib><creatorcontrib>Messina, J</creatorcontrib><creatorcontrib>Comi, G</creatorcontrib><creatorcontrib>Tortorella, C</creatorcontrib><creatorcontrib>Luciannatelli, E</creatorcontrib><creatorcontrib>Senesi, C</creatorcontrib><creatorcontrib>Tsantes, E</creatorcontrib><creatorcontrib>Conti, MZ</creatorcontrib><creatorcontrib>Rottoli, MR</creatorcontrib><creatorcontrib>Bellantonio, P</creatorcontrib><creatorcontrib>Fischetti, M</creatorcontrib><creatorcontrib>Fantozzi, R</creatorcontrib><creatorcontrib>Pala, A</creatorcontrib><creatorcontrib>Traccis, S</creatorcontrib><creatorcontrib>Di Battista, G</creatorcontrib><creatorcontrib>Bianchi, M</creatorcontrib><creatorcontrib>Benedetti, MD</creatorcontrib><creatorcontrib>Gaetani, L</creatorcontrib><creatorcontrib>Di Filippo, M</creatorcontrib><creatorcontrib>Carolei, A</creatorcontrib><creatorcontrib>Totaro, R</creatorcontrib><creatorcontrib>Lanzillo, R</creatorcontrib><creatorcontrib>Brescia Morra, V</creatorcontrib><creatorcontrib>Coppola, R</creatorcontrib><creatorcontrib>Cottone, S</creatorcontrib><creatorcontrib>Chiavazza, C</creatorcontrib><creatorcontrib>Cavalla, P</creatorcontrib><creatorcontrib>Leonardi, C</creatorcontrib><creatorcontrib>Aguglia, U</creatorcontrib><creatorcontrib>Ziuliani, C</creatorcontrib><creatorcontrib>Valla, P</creatorcontrib><creatorcontrib>Sasanelli, F</creatorcontrib><creatorcontrib>Valentino, P</creatorcontrib><creatorcontrib>Quattrone, A</creatorcontrib><creatorcontrib>Martino, Policlinico G.</creatorcontrib><creatorcontrib>Russo, M</creatorcontrib><creatorcontrib>Vita, G</creatorcontrib><creatorcontrib>Immovilli, P</creatorcontrib><creatorcontrib>SIMS-Practice group</creatorcontrib><creatorcontrib>on behalf of the SIMS-Practice group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Multiple sclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Giordano, A</au><au>Lugaresi, A</au><au>Confalonieri, P</au><au>Granella, F</au><au>Radice, D</au><au>Trojano, M</au><au>Martinelli, V</au><au>Solari, A</au><au>Giordano, A</au><au>Martinelli, V</au><au>Lugaresi, A</au><au>Pucci, E</au><au>Granella, F</au><au>Trojano, M</au><au>Solari, A</au><au>Messmer Uccelli, M</au><au>Ferrari, G</au><au>Martini, F</au><au>Radice, D</au><au>D’Annunzio, G</au><au>Farina, D</au><au>Travaglini, D</au><au>Pietrolongo, E</au><au>Onofrj, M</au><au>Torri Clerici, V</au><au>Bonanno, S</au><au>Brambilla, L</au><au>Confalonieri, P</au><au>Radaelli, M</au><au>Messina, J</au><au>Comi, G</au><au>Tortorella, C</au><au>Luciannatelli, E</au><au>Senesi, C</au><au>Tsantes, E</au><au>Conti, MZ</au><au>Rottoli, MR</au><au>Bellantonio, P</au><au>Fischetti, M</au><au>Fantozzi, R</au><au>Pala, A</au><au>Traccis, S</au><au>Di Battista, G</au><au>Bianchi, M</au><au>Benedetti, MD</au><au>Gaetani, L</au><au>Di Filippo, M</au><au>Carolei, A</au><au>Totaro, R</au><au>Lanzillo, R</au><au>Brescia Morra, V</au><au>Coppola, R</au><au>Cottone, S</au><au>Chiavazza, C</au><au>Cavalla, P</au><au>Leonardi, C</au><au>Aguglia, U</au><au>Ziuliani, C</au><au>Valla, P</au><au>Sasanelli, F</au><au>Valentino, P</au><au>Quattrone, A</au><au>Martino, Policlinico G.</au><au>Russo, M</au><au>Vita, G</au><au>Immovilli, P</au><aucorp>SIMS-Practice group</aucorp><aucorp>on behalf of the SIMS-Practice group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Implementation of the ‘Sapere Migliora’ information aid for newly diagnosed people with multiple sclerosis in routine clinical practice: a late-phase controlled trial</atitle><jtitle>Multiple sclerosis</jtitle><addtitle>Mult Scler</addtitle><date>2014-08-01</date><risdate>2014</risdate><volume>20</volume><issue>9</issue><spage>1234</spage><epage>1243</epage><pages>1234-1243</pages><issn>1352-4585</issn><eissn>1477-0970</eissn><abstract>Background:
The SIMS-Trial showed that the ‘Sapere Migliora’ information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction with care.
Objectives:
The objectives of this paper are to assess the effectiveness of the IA in clinical practice and to compare the whole IA with the take-home booklet/website component alone.
Methods:
After updating the IA and replacing the CD with a website, a prospective, open-label non-randomised controlled trial compared the whole IA (group A, five SIMS-Trial centres) to take-home (group B, 16 centres). One month after the intervention, participants completed the MS Knowledge Questionnaire (MSKQ), care satisfaction questionnaire (COSM-R) (primary study outcomes), Hospital and Anxiety Depression Scale, and ad hoc questionnaire appraising the IA.
Results:
We enrolled 159 newly diagnosed PwMS (May 2012–March 2013). Drop-outs were four of 77 (5%, group A) and 11/82 (13%, group B). Primary endpoint (highest tertile both for MSKQ and COSM-R section 2 scores) was achieved by 38/77 (49%) group A and 33/82 (40%) group B (p = 0.25). Attainment of secondary outcomes was also similar between groups.
Conclusions:
This study shows that the entire IA is not superior to the booklet/website alone, and that both are comparable in efficacy to the intervention arm of the SIMS-Trial.
Trial registration number:
ISRCTN78940214.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>24421305</pmid><doi>10.1177/1352458513519180</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1352-4585 |
| ispartof | Multiple sclerosis, 2014-08, Vol.20 (9), p.1234-1243 |
| issn | 1352-4585 1477-0970 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1800701603 |
| source | MEDLINE; SAGE Complete |
| subjects | Adolescent Adult Biological and medical sciences Comprehension Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Health Knowledge, Attitudes, Practice Health Literacy Humans Immunomodulators Internet Interviews as Topic Italy Male Medical sciences Middle Aged Multiple Sclerosis - diagnosis Multiple Sclerosis - physiopathology Multiple Sclerosis - psychology Multiple Sclerosis - therapy Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Patient Education as Topic - methods Patient Satisfaction Pharmacology. Drug treatments Prospective Studies Surveys and Questionnaires Treatment Outcome Young Adult |
| title | Implementation of the ‘Sapere Migliora’ information aid for newly diagnosed people with multiple sclerosis in routine clinical practice: a late-phase controlled trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T20%3A30%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Implementation%20of%20the%20%E2%80%98Sapere%20Migliora%E2%80%99%20information%20aid%20for%20newly%20diagnosed%20people%20with%20multiple%20sclerosis%20in%20routine%20clinical%20practice:%20a%20late-phase%20controlled%20trial&rft.jtitle=Multiple%20sclerosis&rft.au=Giordano,%20A&rft.aucorp=SIMS-Practice%20group&rft.date=2014-08-01&rft.volume=20&rft.issue=9&rft.spage=1234&rft.epage=1243&rft.pages=1234-1243&rft.issn=1352-4585&rft.eissn=1477-0970&rft_id=info:doi/10.1177/1352458513519180&rft_dat=%3Cproquest_cross%3E3368934701%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1544376862&rft_id=info:pmid/24421305&rft_sage_id=10.1177_1352458513519180&rfr_iscdi=true |