Chemical profiling and antioxidant activity of Bolivian propolis
BACKGROUND Propolis is a relevant research subject worldwide. However, there is no information so far on Bolivian propolis. Ten propolis samples were collected from regions with high biodiversity in the main honey production places in Bolivia and were analyzed for their total phenolics (TP), flavono...
Gespeichert in:
| Veröffentlicht in: | Journal of the science of food and agriculture 2016-04, Vol.96 (6), p.2142-2153 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2153 |
|---|---|
| container_issue | 6 |
| container_start_page | 2142 |
| container_title | Journal of the science of food and agriculture |
| container_volume | 96 |
| creator | Nina, Nélida Quispe, Cristina Jiménez-Aspee, Felipe Theoduloz, Cristina Giménez, Alberto Schmeda-Hirschmann, Guillermo |
| description | BACKGROUND
Propolis is a relevant research subject worldwide. However, there is no information so far on Bolivian propolis. Ten propolis samples were collected from regions with high biodiversity in the main honey production places in Bolivia and were analyzed for their total phenolics (TP), flavonoids (TF) and antioxidant activity. The chemical profiles of the samples were assessed by TLC, HPLC‐DAD, HPLC‐DAD‐MS/MSn and NMR analysis.
RESULTS
TP, TF, TLC and NMR analysis showed significant chemical differences between the samples. Isolation of the main constituents by chromatography and identification by HPLC‐DAD‐MS/MSn achieved more than 35 constituents. According to their profiles, the Bolivian propolis can be classified into phenolic‐rich and triterpene‐rich samples. Propolis from the valleys (Cochabamba, Chuquisaca and Tarija) contained mainly prenylated phenylpropanoids, while samples from La Paz and Santa Cruz contained cycloartane and pentacyclic triterpenes. Phenolic‐rich samples presented moderate to strong antioxidant activity while the triterpene‐rich propolis were weakly active.
CONCLUSION
High chemical diversity and differential antioxidant effects were found in Bolivian propolis. Our results provide additional evidence on the chemical composition and bioactivity of South American propolis. © 2015 Society of Chemical Industry |
| doi_str_mv | 10.1002/jsfa.7330 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1800502152</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3975346301</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4240-e3ac553a8a79816a0692f162b30e3c80c6e76a8f0425a7093acf18ad4528ff573</originalsourceid><addsrcrecordid>eNqF0clOwzAQBmALgaAsB14AReICh8DYjrcbtGIVYt9ulkltcEmTEqdA3x5HLRyQEAdrLPmb37IHoXUMOxiA7A6CMzuCUphDHQxKpAAY5lEnnpGU4YwsoeUQBgCgFOeLaIlwTCXlooP2ei926HNTJKO6cr7w5XNiyn5cja8-fT_WxOSNf_fNJKlc0q2KuDdly0dxH1bRgjNFsGuzuoLuDg9ue8fp2cXRSW__LM0zkkFqqckZo0YaoSTmBrgiDnPyRMHSXELOreBGOsgIMwJU5A5L088Ykc4xQVfQ1jQ3Xvw2tqHRQx9yWxSmtNU4aCwBGBDMyP9UCCIpEwpHuvmLDqpxXcaHtAozpYBAVNtTlddVCLV1elT7oaknGoNuJ6DbCeh2AtFuzBLHT0Pb_5HfXx7B7hR8-MJO_k7SpzeH-7PIdNrhQ2M_fzpM_apjnmD64fxIX2fweH912dVd-gVXm50N</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1771599020</pqid></control><display><type>article</type><title>Chemical profiling and antioxidant activity of Bolivian propolis</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Nina, Nélida ; Quispe, Cristina ; Jiménez-Aspee, Felipe ; Theoduloz, Cristina ; Giménez, Alberto ; Schmeda-Hirschmann, Guillermo</creator><creatorcontrib>Nina, Nélida ; Quispe, Cristina ; Jiménez-Aspee, Felipe ; Theoduloz, Cristina ; Giménez, Alberto ; Schmeda-Hirschmann, Guillermo</creatorcontrib><description>BACKGROUND
Propolis is a relevant research subject worldwide. However, there is no information so far on Bolivian propolis. Ten propolis samples were collected from regions with high biodiversity in the main honey production places in Bolivia and were analyzed for their total phenolics (TP), flavonoids (TF) and antioxidant activity. The chemical profiles of the samples were assessed by TLC, HPLC‐DAD, HPLC‐DAD‐MS/MSn and NMR analysis.
RESULTS
TP, TF, TLC and NMR analysis showed significant chemical differences between the samples. Isolation of the main constituents by chromatography and identification by HPLC‐DAD‐MS/MSn achieved more than 35 constituents. According to their profiles, the Bolivian propolis can be classified into phenolic‐rich and triterpene‐rich samples. Propolis from the valleys (Cochabamba, Chuquisaca and Tarija) contained mainly prenylated phenylpropanoids, while samples from La Paz and Santa Cruz contained cycloartane and pentacyclic triterpenes. Phenolic‐rich samples presented moderate to strong antioxidant activity while the triterpene‐rich propolis were weakly active.
CONCLUSION
High chemical diversity and differential antioxidant effects were found in Bolivian propolis. Our results provide additional evidence on the chemical composition and bioactivity of South American propolis. © 2015 Society of Chemical Industry</description><identifier>ISSN: 0022-5142</identifier><identifier>EISSN: 1097-0010</identifier><identifier>DOI: 10.1002/jsfa.7330</identifier><identifier>PMID: 26138367</identifier><identifier>CODEN: JSFAAE</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>antioxidant ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - pharmacology ; artepillin C ; Biochemistry ; Biphenyl Compounds ; Bolivia ; Chromatography - methods ; Constituents ; Ferric Compounds - chemistry ; Flavonoids - chemistry ; Food science ; Foods ; Honey ; Molecular Structure ; Nuclear magnetic resonance ; Phenols - chemistry ; phenylpropanoids ; Picrates ; Propolis ; Propolis - chemistry ; Propolis - pharmacology ; Spectrometry, Mass, Electrospray Ionization - methods ; Tandem Mass Spectrometry - methods ; triterpenes</subject><ispartof>Journal of the science of food and agriculture, 2016-04, Vol.96 (6), p.2142-2153</ispartof><rights>2015 Society of Chemical Industry</rights><rights>2015 Society of Chemical Industry.</rights><rights>2016 Society of Chemical Industry</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4240-e3ac553a8a79816a0692f162b30e3c80c6e76a8f0425a7093acf18ad4528ff573</citedby><cites>FETCH-LOGICAL-c4240-e3ac553a8a79816a0692f162b30e3c80c6e76a8f0425a7093acf18ad4528ff573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjsfa.7330$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjsfa.7330$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26138367$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nina, Nélida</creatorcontrib><creatorcontrib>Quispe, Cristina</creatorcontrib><creatorcontrib>Jiménez-Aspee, Felipe</creatorcontrib><creatorcontrib>Theoduloz, Cristina</creatorcontrib><creatorcontrib>Giménez, Alberto</creatorcontrib><creatorcontrib>Schmeda-Hirschmann, Guillermo</creatorcontrib><title>Chemical profiling and antioxidant activity of Bolivian propolis</title><title>Journal of the science of food and agriculture</title><addtitle>J. Sci. Food Agric</addtitle><description>BACKGROUND
Propolis is a relevant research subject worldwide. However, there is no information so far on Bolivian propolis. Ten propolis samples were collected from regions with high biodiversity in the main honey production places in Bolivia and were analyzed for their total phenolics (TP), flavonoids (TF) and antioxidant activity. The chemical profiles of the samples were assessed by TLC, HPLC‐DAD, HPLC‐DAD‐MS/MSn and NMR analysis.
RESULTS
TP, TF, TLC and NMR analysis showed significant chemical differences between the samples. Isolation of the main constituents by chromatography and identification by HPLC‐DAD‐MS/MSn achieved more than 35 constituents. According to their profiles, the Bolivian propolis can be classified into phenolic‐rich and triterpene‐rich samples. Propolis from the valleys (Cochabamba, Chuquisaca and Tarija) contained mainly prenylated phenylpropanoids, while samples from La Paz and Santa Cruz contained cycloartane and pentacyclic triterpenes. Phenolic‐rich samples presented moderate to strong antioxidant activity while the triterpene‐rich propolis were weakly active.
CONCLUSION
High chemical diversity and differential antioxidant effects were found in Bolivian propolis. Our results provide additional evidence on the chemical composition and bioactivity of South American propolis. © 2015 Society of Chemical Industry</description><subject>antioxidant</subject><subject>Antioxidants</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>artepillin C</subject><subject>Biochemistry</subject><subject>Biphenyl Compounds</subject><subject>Bolivia</subject><subject>Chromatography - methods</subject><subject>Constituents</subject><subject>Ferric Compounds - chemistry</subject><subject>Flavonoids - chemistry</subject><subject>Food science</subject><subject>Foods</subject><subject>Honey</subject><subject>Molecular Structure</subject><subject>Nuclear magnetic resonance</subject><subject>Phenols - chemistry</subject><subject>phenylpropanoids</subject><subject>Picrates</subject><subject>Propolis</subject><subject>Propolis - chemistry</subject><subject>Propolis - pharmacology</subject><subject>Spectrometry, Mass, Electrospray Ionization - methods</subject><subject>Tandem Mass Spectrometry - methods</subject><subject>triterpenes</subject><issn>0022-5142</issn><issn>1097-0010</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0clOwzAQBmALgaAsB14AReICh8DYjrcbtGIVYt9ulkltcEmTEqdA3x5HLRyQEAdrLPmb37IHoXUMOxiA7A6CMzuCUphDHQxKpAAY5lEnnpGU4YwsoeUQBgCgFOeLaIlwTCXlooP2ei926HNTJKO6cr7w5XNiyn5cja8-fT_WxOSNf_fNJKlc0q2KuDdly0dxH1bRgjNFsGuzuoLuDg9ue8fp2cXRSW__LM0zkkFqqckZo0YaoSTmBrgiDnPyRMHSXELOreBGOsgIMwJU5A5L088Ykc4xQVfQ1jQ3Xvw2tqHRQx9yWxSmtNU4aCwBGBDMyP9UCCIpEwpHuvmLDqpxXcaHtAozpYBAVNtTlddVCLV1elT7oaknGoNuJ6DbCeh2AtFuzBLHT0Pb_5HfXx7B7hR8-MJO_k7SpzeH-7PIdNrhQ2M_fzpM_apjnmD64fxIX2fweH912dVd-gVXm50N</recordid><startdate>201604</startdate><enddate>201604</enddate><creator>Nina, Nélida</creator><creator>Quispe, Cristina</creator><creator>Jiménez-Aspee, Felipe</creator><creator>Theoduloz, Cristina</creator><creator>Giménez, Alberto</creator><creator>Schmeda-Hirschmann, Guillermo</creator><general>John Wiley & Sons, Ltd</general><general>John Wiley and Sons, Limited</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QL</scope><scope>7QQ</scope><scope>7QR</scope><scope>7SC</scope><scope>7SE</scope><scope>7SN</scope><scope>7SP</scope><scope>7SR</scope><scope>7ST</scope><scope>7T5</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7U5</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>M7N</scope><scope>P64</scope><scope>SOI</scope><scope>7X8</scope></search><sort><creationdate>201604</creationdate><title>Chemical profiling and antioxidant activity of Bolivian propolis</title><author>Nina, Nélida ; Quispe, Cristina ; Jiménez-Aspee, Felipe ; Theoduloz, Cristina ; Giménez, Alberto ; Schmeda-Hirschmann, Guillermo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4240-e3ac553a8a79816a0692f162b30e3c80c6e76a8f0425a7093acf18ad4528ff573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>antioxidant</topic><topic>Antioxidants</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>artepillin C</topic><topic>Biochemistry</topic><topic>Biphenyl Compounds</topic><topic>Bolivia</topic><topic>Chromatography - methods</topic><topic>Constituents</topic><topic>Ferric Compounds - chemistry</topic><topic>Flavonoids - chemistry</topic><topic>Food science</topic><topic>Foods</topic><topic>Honey</topic><topic>Molecular Structure</topic><topic>Nuclear magnetic resonance</topic><topic>Phenols - chemistry</topic><topic>phenylpropanoids</topic><topic>Picrates</topic><topic>Propolis</topic><topic>Propolis - chemistry</topic><topic>Propolis - pharmacology</topic><topic>Spectrometry, Mass, Electrospray Ionization - methods</topic><topic>Tandem Mass Spectrometry - methods</topic><topic>triterpenes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nina, Nélida</creatorcontrib><creatorcontrib>Quispe, Cristina</creatorcontrib><creatorcontrib>Jiménez-Aspee, Felipe</creatorcontrib><creatorcontrib>Theoduloz, Cristina</creatorcontrib><creatorcontrib>Giménez, Alberto</creatorcontrib><creatorcontrib>Schmeda-Hirschmann, Guillermo</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Ceramic Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Ecology Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the science of food and agriculture</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nina, Nélida</au><au>Quispe, Cristina</au><au>Jiménez-Aspee, Felipe</au><au>Theoduloz, Cristina</au><au>Giménez, Alberto</au><au>Schmeda-Hirschmann, Guillermo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chemical profiling and antioxidant activity of Bolivian propolis</atitle><jtitle>Journal of the science of food and agriculture</jtitle><addtitle>J. Sci. Food Agric</addtitle><date>2016-04</date><risdate>2016</risdate><volume>96</volume><issue>6</issue><spage>2142</spage><epage>2153</epage><pages>2142-2153</pages><issn>0022-5142</issn><eissn>1097-0010</eissn><coden>JSFAAE</coden><abstract>BACKGROUND
Propolis is a relevant research subject worldwide. However, there is no information so far on Bolivian propolis. Ten propolis samples were collected from regions with high biodiversity in the main honey production places in Bolivia and were analyzed for their total phenolics (TP), flavonoids (TF) and antioxidant activity. The chemical profiles of the samples were assessed by TLC, HPLC‐DAD, HPLC‐DAD‐MS/MSn and NMR analysis.
RESULTS
TP, TF, TLC and NMR analysis showed significant chemical differences between the samples. Isolation of the main constituents by chromatography and identification by HPLC‐DAD‐MS/MSn achieved more than 35 constituents. According to their profiles, the Bolivian propolis can be classified into phenolic‐rich and triterpene‐rich samples. Propolis from the valleys (Cochabamba, Chuquisaca and Tarija) contained mainly prenylated phenylpropanoids, while samples from La Paz and Santa Cruz contained cycloartane and pentacyclic triterpenes. Phenolic‐rich samples presented moderate to strong antioxidant activity while the triterpene‐rich propolis were weakly active.
CONCLUSION
High chemical diversity and differential antioxidant effects were found in Bolivian propolis. Our results provide additional evidence on the chemical composition and bioactivity of South American propolis. © 2015 Society of Chemical Industry</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>26138367</pmid><doi>10.1002/jsfa.7330</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-5142 |
| ispartof | Journal of the science of food and agriculture, 2016-04, Vol.96 (6), p.2142-2153 |
| issn | 0022-5142 1097-0010 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1800502152 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | antioxidant Antioxidants Antioxidants - chemistry Antioxidants - pharmacology artepillin C Biochemistry Biphenyl Compounds Bolivia Chromatography - methods Constituents Ferric Compounds - chemistry Flavonoids - chemistry Food science Foods Honey Molecular Structure Nuclear magnetic resonance Phenols - chemistry phenylpropanoids Picrates Propolis Propolis - chemistry Propolis - pharmacology Spectrometry, Mass, Electrospray Ionization - methods Tandem Mass Spectrometry - methods triterpenes |
| title | Chemical profiling and antioxidant activity of Bolivian propolis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T21%3A35%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Chemical%20profiling%20and%20antioxidant%20activity%20of%20Bolivian%20propolis&rft.jtitle=Journal%20of%20the%20science%20of%20food%20and%20agriculture&rft.au=Nina,%20N%C3%A9lida&rft.date=2016-04&rft.volume=96&rft.issue=6&rft.spage=2142&rft.epage=2153&rft.pages=2142-2153&rft.issn=0022-5142&rft.eissn=1097-0010&rft.coden=JSFAAE&rft_id=info:doi/10.1002/jsfa.7330&rft_dat=%3Cproquest_cross%3E3975346301%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1771599020&rft_id=info:pmid/26138367&rfr_iscdi=true |