Charge-selective claudin channels

Claudins are the main determinants of barrier properties of the tight junction. Many claudins have been shown to act by tightening the paracellular pathway, but several function as paracellular channels. While some depend on the endogenous claudin background of the analyzed cell line, for other clau...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2012-06, Vol.1257 (1), p.20-28
Hauptverfasser:	Krug, Susanne M., Günzel, Dorothee, Conrad, Marcel P., Lee, In-Fah M., Amasheh, Salah, Fromm, Michael, Yu, Alan S. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological Transport - physiology Biotechnology Cations Channels Chlorides claudin-10a claudin-10b claudin-15 claudin-17 claudin-2 Claudins - chemistry Claudins - metabolism Intestines Kidneys Membrane Proteins - metabolism Molecular Sequence Data Pathways pore properties Small intestine Sodium Tight Junctions - metabolism Tightening
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