Isolation of nucleated red blood cells in maternal blood for Non-invasive prenatal diagnosis

This paper introduces a two-step cascade enrichment method for isolating nucleated red blood cells (NRBCs) in maternal blood. The two-step enrichment platform consists of a positive enrichment process based on a red blood cell (RBC) hyperaggregation method and a negative enrichment process using mic...

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Veröffentlicht in:	Biomedical microdevices 2015-12, Vol.17 (6), p.118-7, Article 118
Hauptverfasser:	Byeon, Yeongje, Ki, Chang-Seok, Han, Ki-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Blood Blood cells Cascades Cell Separation Cells Depletion Engineering Engineering Fluid Dynamics Enrichment Equipment Design Erythroblasts - cytology Erythrocyte Count Erythrocytes - cytology Female Fetal Blood Genes Humans Leukocytes - cytology Male Maternal & child health Mathematical analysis Medical diagnosis Nanotechnology Pregnancy Prenatal development Prenatal Diagnosis - methods Red blood cells Sex-Determining Region Y Protein - genetics
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