Use of Three-Dimensional Arterial Models To Predict the In Vivo Behavior of Nanoparticles for Drug Delivery

Nanomaterials have been widely used for applications in biomedical fields and could become indispensable in the near future. However, since it is difficult to optimize in vivo biological behavior in a 3D environment by using a single cell in vitro, there have been many failures in animal models. In ...

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Veröffentlicht in:	Angewandte Chemie 2016-03, Vol.128 (14), p.4537-4542
Hauptverfasser:	Chetprayoon, Paninee, Matsusaki, Michiya, Yokoyama, Utako, Tejima, Takanori, Ishikawa, Yoshihiro, Akashi, Mitsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Biomedical materials Chemistry Drug delivery systems Dünne Filme Mathematical models Nanomaterials Nanoparticles Nanopartikel Optimization Schichtverbindungen Three dimensional models Wirkstofftransport Zelladhäsion
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