Sulfonyl Fluoride-Based Prosthetic Compounds as Potential super(18)F Labelling Agents

Nucleophilic incorporation of [ super(18)F]F super(-) under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the advent of complex biological pharmacophores. Sulfonyl fluorides can be prepared in water at room temperature, yet they have not been assayed...

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Veröffentlicht in:	Chemistry : a European journal 2012-08, Vol.18 (35), p.11079-11087
Hauptverfasser:	Inkster, James AH, Liu, Kate, Ait-Mohand, Samia, Schaffer, Paul, Guerin, Brigitte, Ruth, Thomas J, Storr, Tim
Format:	Artikel
Sprache:	eng
Schlagworte:	Chlorides Degradation Fluorides Labelling Precursors Prosthetics Pyridines Strategy
Online-Zugang:	Volltext
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