Palladium-Catalyzed Arylation of Unactivated γ-Methylene C(sp3)H and δ-CH Bonds with an Oxazoline-Carboxylate Auxiliary

A palladium‐catalyzed arylation of unactivated γ‐methylene C(sp3)H and remote δ‐CH bonds by using an oxazoline‐carboxylate directing group has been developed. Arylation occurs with a broad substrate scope and high tolerance of functional groups (i.e., halogen, nitro, cyano, ether, trifluoromethyl,...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemistry : a European journal 2015-11, Vol.21 (48), p.17503-17507
Hauptverfasser:	Ling, Peng-Xiang, Fang, Sheng-Long, Yin, Xue-Song, Chen, Kai, Sun, Bo-Zheng, Shi, Bing-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines arylation Construction CH activation directing groups Esters Ethers Functional groups Halogens oxazolines palladium Substrates Tolerances
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!