Intra-articular delivery of a methotrexate loaded nanostructured lipid carrier based smart gel for effective treatment of rheumatic diseases

A nanostructured lipid carrier (NLC) based smart gel of methotrexate (MTX) was developed as a potential system for the treatment of rheumatic diseases (RD). NLC composed of Compritol ATO 888 as the solid lipid, Capmul MCM EP as the liquid lipid, Tween 80 as the surfactant and PEG 400 as the co-surfa...

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Veröffentlicht in:	RSC advances 2016-01, Vol.6 (16), p.12913-12924
Hauptverfasser:	Shinde, Chetan G, Pramod kumar, T. M, Venkatesh, M. P, Rajesh, K. S, Srivastava, Atul, Osmani, Riyaz Ali M, Sonawane, Yogesh H
Format:	Artikel
Sprache:	eng
Schlagworte:	Carriers Dispersions Homogenizing Lipids Mathematical models Medical services Nanostructure Zeta potential
Online-Zugang:	Volltext
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