A coumarin-based fluorescent turn-on probe for detection of biothiols in vitro

A novel fluorescent probe (CA‐N) was designed and synthesized for detection of biothiols. CA‐N displayed a strong fluorescence in the presence of biothiols with high sensitivity, and the mechanism for detection biothiols was based on the Michael addition reaction of a thiol group to α,β‐unsaturated...

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Veröffentlicht in:	Luminescence (Chichester, England) England), 2015-12, Vol.30 (8), p.1395-1402
Hauptverfasser:	Liu, Mengqiang, Jiang, Qian, Lu, Zhiyun, Huang, Yan, Tan, Yanfei, Jiang, Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids bioimaging Cell Line Cells (biology) Cells - chemistry Cells - metabolism coumarin Coumarins - chemistry Fluorescence Fluorescent Dyes - chemical synthesis Fluorescent Dyes - chemistry fluorescent probe Humans In vitro testing Ketones Limit of Detection Luminescence Mathematical analysis Michael addition Michael reaction Spectrometry, Fluorescence - methods Sulfhydryl Compounds - analysis Sulfhydryl Compounds - metabolism
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