Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties
Development of functional biomaterials by a design‐driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability...
Gespeichert in:
| Veröffentlicht in: | Advanced materials (Weinheim) 2016-03, Vol.28 (9), p.1803-1808 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1808 |
|---|---|
| container_issue | 9 |
| container_start_page | 1803 |
| container_title | Advanced materials (Weinheim) |
| container_volume | 28 |
| creator | Danoux, Charlène Sun, Lanying Koçer, Gülistan Birgani, Zeinab Tahmasebi Barata, David Barralet, Jake van Blitterswijk, Clemens Truckenmüller, Roman Habibovic, Pamela |
| description | Development of functional biomaterials by a design‐driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing‐driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it. |
| doi_str_mv | 10.1002/adma.201504589 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1800473984</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1769982804</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5639-a5920c3ab17ae787fddd93230f9cad23b83d0d24383ebc8de51a899c3990ae903</originalsourceid><addsrcrecordid>eNqFkM9v1DAQhS0EokvhyhHlyCXL2I4dz3Hp0hbUQmlBHC0nnhRDfjVOoPvfk9Uuq956Gj3p-540j7HXHJYcQLxzvnFLAVxBpgw-YQuuBE8zQPWULQClSlFn5oi9iPEXAKAG_ZwdCa0NmixfMLumP1R3fUPtmHRVch5uf9ab5HRqyzF0rauT96Fr3EhDcHVMik2yprKb-jq0t4lrfXI9x6YI7TZf7rnkauh6GsZA8SV7Vs0ivdrfY_b99MO3k_P04svZx5PVRVoqLTF1CgWU0hU8d5SbvPLeoxQSKiydF7Iw0oMXmTSSitJ4UtwZxFIigiMEecze7nr7obubKI62CbGkunYtdVO03ABkuZyffhzNNaIRBrbocoeWQxfjQJXth9C4YWM52O3-dru_Pew_C2_23VPRkD_g_wefAdwBf0NNm0fq7Gp9uXpYnu7cEEe6P7hu-G11LnNlf3w-s_KT1F-vbqTV8h-Sv6GC</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1769982804</pqid></control><display><type>article</type><title>Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties</title><source>Wiley-Blackwell Journals</source><source>MEDLINE</source><creator>Danoux, Charlène ; Sun, Lanying ; Koçer, Gülistan ; Birgani, Zeinab Tahmasebi ; Barata, David ; Barralet, Jake ; van Blitterswijk, Clemens ; Truckenmüller, Roman ; Habibovic, Pamela</creator><creatorcontrib>Danoux, Charlène ; Sun, Lanying ; Koçer, Gülistan ; Birgani, Zeinab Tahmasebi ; Barata, David ; Barralet, Jake ; van Blitterswijk, Clemens ; Truckenmüller, Roman ; Habibovic, Pamela</creatorcontrib><description>Development of functional biomaterials by a design‐driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing‐driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.</description><identifier>ISSN: 0935-9648</identifier><identifier>EISSN: 1521-4095</identifier><identifier>DOI: 10.1002/adma.201504589</identifier><identifier>PMID: 26689847</identifier><language>eng</language><publisher>Germany: Blackwell Publishing Ltd</publisher><subject>Biocompatible Materials - chemistry ; Biocompatible Materials - pharmacology ; Biological ; Biomaterials ; Biomedical materials ; Bone Morphogenetic Protein 2 - genetics ; calcium phosphates ; Calcium Phosphates - chemistry ; composites ; Decoupling ; Drug Design ; Elastomers - chemistry ; Gene Expression Regulation - drug effects ; Humans ; Mesenchymal Stromal Cells - drug effects ; Mesenchymal Stromal Cells - metabolism ; Models, Molecular ; Molecular Conformation ; nanoimprinting ; osteogenic differentiation ; Osteopontin - genetics ; property-function relationships ; Sole ; Surface Properties ; Surgical implants</subject><ispartof>Advanced materials (Weinheim), 2016-03, Vol.28 (9), p.1803-1808</ispartof><rights>2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5639-a5920c3ab17ae787fddd93230f9cad23b83d0d24383ebc8de51a899c3990ae903</citedby><cites>FETCH-LOGICAL-c5639-a5920c3ab17ae787fddd93230f9cad23b83d0d24383ebc8de51a899c3990ae903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fadma.201504589$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fadma.201504589$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26689847$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Danoux, Charlène</creatorcontrib><creatorcontrib>Sun, Lanying</creatorcontrib><creatorcontrib>Koçer, Gülistan</creatorcontrib><creatorcontrib>Birgani, Zeinab Tahmasebi</creatorcontrib><creatorcontrib>Barata, David</creatorcontrib><creatorcontrib>Barralet, Jake</creatorcontrib><creatorcontrib>van Blitterswijk, Clemens</creatorcontrib><creatorcontrib>Truckenmüller, Roman</creatorcontrib><creatorcontrib>Habibovic, Pamela</creatorcontrib><title>Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties</title><title>Advanced materials (Weinheim)</title><addtitle>Adv. Mater</addtitle><description>Development of functional biomaterials by a design‐driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing‐driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.</description><subject>Biocompatible Materials - chemistry</subject><subject>Biocompatible Materials - pharmacology</subject><subject>Biological</subject><subject>Biomaterials</subject><subject>Biomedical materials</subject><subject>Bone Morphogenetic Protein 2 - genetics</subject><subject>calcium phosphates</subject><subject>Calcium Phosphates - chemistry</subject><subject>composites</subject><subject>Decoupling</subject><subject>Drug Design</subject><subject>Elastomers - chemistry</subject><subject>Gene Expression Regulation - drug effects</subject><subject>Humans</subject><subject>Mesenchymal Stromal Cells - drug effects</subject><subject>Mesenchymal Stromal Cells - metabolism</subject><subject>Models, Molecular</subject><subject>Molecular Conformation</subject><subject>nanoimprinting</subject><subject>osteogenic differentiation</subject><subject>Osteopontin - genetics</subject><subject>property-function relationships</subject><subject>Sole</subject><subject>Surface Properties</subject><subject>Surgical implants</subject><issn>0935-9648</issn><issn>1521-4095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9v1DAQhS0EokvhyhHlyCXL2I4dz3Hp0hbUQmlBHC0nnhRDfjVOoPvfk9Uuq956Gj3p-540j7HXHJYcQLxzvnFLAVxBpgw-YQuuBE8zQPWULQClSlFn5oi9iPEXAKAG_ZwdCa0NmixfMLumP1R3fUPtmHRVch5uf9ab5HRqyzF0rauT96Fr3EhDcHVMik2yprKb-jq0t4lrfXI9x6YI7TZf7rnkauh6GsZA8SV7Vs0ivdrfY_b99MO3k_P04svZx5PVRVoqLTF1CgWU0hU8d5SbvPLeoxQSKiydF7Iw0oMXmTSSitJ4UtwZxFIigiMEecze7nr7obubKI62CbGkunYtdVO03ABkuZyffhzNNaIRBrbocoeWQxfjQJXth9C4YWM52O3-dru_Pew_C2_23VPRkD_g_wefAdwBf0NNm0fq7Gp9uXpYnu7cEEe6P7hu-G11LnNlf3w-s_KT1F-vbqTV8h-Sv6GC</recordid><startdate>20160302</startdate><enddate>20160302</enddate><creator>Danoux, Charlène</creator><creator>Sun, Lanying</creator><creator>Koçer, Gülistan</creator><creator>Birgani, Zeinab Tahmasebi</creator><creator>Barata, David</creator><creator>Barralet, Jake</creator><creator>van Blitterswijk, Clemens</creator><creator>Truckenmüller, Roman</creator><creator>Habibovic, Pamela</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>20160302</creationdate><title>Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties</title><author>Danoux, Charlène ; Sun, Lanying ; Koçer, Gülistan ; Birgani, Zeinab Tahmasebi ; Barata, David ; Barralet, Jake ; van Blitterswijk, Clemens ; Truckenmüller, Roman ; Habibovic, Pamela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5639-a5920c3ab17ae787fddd93230f9cad23b83d0d24383ebc8de51a899c3990ae903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Biocompatible Materials - chemistry</topic><topic>Biocompatible Materials - pharmacology</topic><topic>Biological</topic><topic>Biomaterials</topic><topic>Biomedical materials</topic><topic>Bone Morphogenetic Protein 2 - genetics</topic><topic>calcium phosphates</topic><topic>Calcium Phosphates - chemistry</topic><topic>composites</topic><topic>Decoupling</topic><topic>Drug Design</topic><topic>Elastomers - chemistry</topic><topic>Gene Expression Regulation - drug effects</topic><topic>Humans</topic><topic>Mesenchymal Stromal Cells - drug effects</topic><topic>Mesenchymal Stromal Cells - metabolism</topic><topic>Models, Molecular</topic><topic>Molecular Conformation</topic><topic>nanoimprinting</topic><topic>osteogenic differentiation</topic><topic>Osteopontin - genetics</topic><topic>property-function relationships</topic><topic>Sole</topic><topic>Surface Properties</topic><topic>Surgical implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Danoux, Charlène</creatorcontrib><creatorcontrib>Sun, Lanying</creatorcontrib><creatorcontrib>Koçer, Gülistan</creatorcontrib><creatorcontrib>Birgani, Zeinab Tahmasebi</creatorcontrib><creatorcontrib>Barata, David</creatorcontrib><creatorcontrib>Barralet, Jake</creatorcontrib><creatorcontrib>van Blitterswijk, Clemens</creatorcontrib><creatorcontrib>Truckenmüller, Roman</creatorcontrib><creatorcontrib>Habibovic, Pamela</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Advanced materials (Weinheim)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Danoux, Charlène</au><au>Sun, Lanying</au><au>Koçer, Gülistan</au><au>Birgani, Zeinab Tahmasebi</au><au>Barata, David</au><au>Barralet, Jake</au><au>van Blitterswijk, Clemens</au><au>Truckenmüller, Roman</au><au>Habibovic, Pamela</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties</atitle><jtitle>Advanced materials (Weinheim)</jtitle><addtitle>Adv. Mater</addtitle><date>2016-03-02</date><risdate>2016</risdate><volume>28</volume><issue>9</issue><spage>1803</spage><epage>1808</epage><pages>1803-1808</pages><issn>0935-9648</issn><eissn>1521-4095</eissn><abstract>Development of functional biomaterials by a design‐driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing‐driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.</abstract><cop>Germany</cop><pub>Blackwell Publishing Ltd</pub><pmid>26689847</pmid><doi>10.1002/adma.201504589</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0935-9648 |
| ispartof | Advanced materials (Weinheim), 2016-03, Vol.28 (9), p.1803-1808 |
| issn | 0935-9648 1521-4095 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1800473984 |
| source | Wiley-Blackwell Journals; MEDLINE |
| subjects | Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Biological Biomaterials Biomedical materials Bone Morphogenetic Protein 2 - genetics calcium phosphates Calcium Phosphates - chemistry composites Decoupling Drug Design Elastomers - chemistry Gene Expression Regulation - drug effects Humans Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Models, Molecular Molecular Conformation nanoimprinting osteogenic differentiation Osteopontin - genetics property-function relationships Sole Surface Properties Surgical implants |
| title | Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T16%3A16%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20of%20Highly%20Functional%20Biomaterials%20by%20Decoupling%20and%20Recombining%20Material%20Properties&rft.jtitle=Advanced%20materials%20(Weinheim)&rft.au=Danoux,%20Charl%C3%A8ne&rft.date=2016-03-02&rft.volume=28&rft.issue=9&rft.spage=1803&rft.epage=1808&rft.pages=1803-1808&rft.issn=0935-9648&rft.eissn=1521-4095&rft_id=info:doi/10.1002/adma.201504589&rft_dat=%3Cproquest_cross%3E1769982804%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1769982804&rft_id=info:pmid/26689847&rfr_iscdi=true |