Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells

To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. Although digalactosyldiacylglycerol and sulfoquinovosyldiacylglycerol suppressed fuco...

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Veröffentlicht in:Journal of Oleo Science 2015, Vol.64(11), pp.1207-1211
Hauptverfasser: Kotake-Nara, Eiichi, Yonekura, Lina, Nagao, Akihiko
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creator Kotake-Nara, Eiichi
Yonekura, Lina
Nagao, Akihiko
description To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. Although digalactosyldiacylglycerol and sulfoquinovosyldiacylglycerol suppressed fucoxanthin uptake and secretion, their lyso-types, digalactosylmonoacylglycerol and sulfoquinovosylmonoa cylglycerol, remarkably enhanced them. Thus, some dietary glyceroglycolipids may be potential enhancers of fucoxanthin bioavailability in humans.
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source MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry
subjects Bioavailability
Biological Availability
Caco-2
Caco-2 Cells
Dietary Supplements
fucoxanthin
glyceroglycolipid
Glycolipids - pharmacology
Human
Humans
intestinal absorption
Intestinal Absorption - drug effects
Micelles
mixed micelles
Secretions
Solubility
Uptakes
Xanthophylls - chemistry
Xanthophylls - metabolism
title Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells
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