Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells
To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. Although digalactosyldiacylglycerol and sulfoquinovosyldiacylglycerol suppressed fuco...
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Veröffentlicht in: | Journal of Oleo Science 2015, Vol.64(11), pp.1207-1211 |
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creator | Kotake-Nara, Eiichi Yonekura, Lina Nagao, Akihiko |
description | To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. Although digalactosyldiacylglycerol and sulfoquinovosyldiacylglycerol suppressed fucoxanthin uptake and secretion, their lyso-types, digalactosylmonoacylglycerol and sulfoquinovosylmonoa cylglycerol, remarkably enhanced them. Thus, some dietary glyceroglycolipids may be potential enhancers of fucoxanthin bioavailability in humans. |
doi_str_mv | 10.5650/jos.ess15180 |
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Although digalactosyldiacylglycerol and sulfoquinovosyldiacylglycerol suppressed fucoxanthin uptake and secretion, their lyso-types, digalactosylmonoacylglycerol and sulfoquinovosylmonoa cylglycerol, remarkably enhanced them. Thus, some dietary glyceroglycolipids may be potential enhancers of fucoxanthin bioavailability in humans.</description><identifier>ISSN: 1345-8957</identifier><identifier>EISSN: 1347-3352</identifier><identifier>DOI: 10.5650/jos.ess15180</identifier><identifier>PMID: 26468234</identifier><language>eng</language><publisher>Japan: Japan Oil Chemists' Society</publisher><subject>Bioavailability ; Biological Availability ; Caco-2 ; Caco-2 Cells ; Dietary Supplements ; fucoxanthin ; glyceroglycolipid ; Glycolipids - pharmacology ; Human ; Humans ; intestinal absorption ; Intestinal Absorption - drug effects ; Micelles ; mixed micelles ; Secretions ; Solubility ; Uptakes ; Xanthophylls - chemistry ; Xanthophylls - metabolism</subject><ispartof>Journal of Oleo Science, 2015, Vol.64(11), pp.1207-1211</ispartof><rights>2015 by Japan Oil Chemists' Society</rights><rights>Copyright Japan Science and Technology Agency 2015</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c688t-bd69020bf20e8df9c94577b4f23d74d9183294b97e665fceaa4a35f484c888ad3</citedby><cites>FETCH-LOGICAL-c688t-bd69020bf20e8df9c94577b4f23d74d9183294b97e665fceaa4a35f484c888ad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26468234$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kotake-Nara, Eiichi</creatorcontrib><creatorcontrib>Yonekura, Lina</creatorcontrib><creatorcontrib>Nagao, Akihiko</creatorcontrib><creatorcontrib>National Food Research Institute</creatorcontrib><creatorcontrib>National Agriculture and Food Research Organization</creatorcontrib><title>Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells</title><title>Journal of Oleo Science</title><addtitle>J Oleo Sci</addtitle><description>To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. 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Thus, some dietary glyceroglycolipids may be potential enhancers of fucoxanthin bioavailability in humans.</description><subject>Bioavailability</subject><subject>Biological Availability</subject><subject>Caco-2</subject><subject>Caco-2 Cells</subject><subject>Dietary Supplements</subject><subject>fucoxanthin</subject><subject>glyceroglycolipid</subject><subject>Glycolipids - pharmacology</subject><subject>Human</subject><subject>Humans</subject><subject>intestinal absorption</subject><subject>Intestinal Absorption - drug effects</subject><subject>Micelles</subject><subject>mixed micelles</subject><subject>Secretions</subject><subject>Solubility</subject><subject>Uptakes</subject><subject>Xanthophylls - chemistry</subject><subject>Xanthophylls - metabolism</subject><issn>1345-8957</issn><issn>1347-3352</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEtv1DAUhS1E1RfdsUaW2LAgxW87yyqi7UhTsYG1cRyn48gTD3aCmH-Pm-kMEhtfy_e75x4fAN5jdMsFR1-GmG9dzphjhd6AS0yZrCjl5O1y55WqubwAVzkPCJV3Ls_BBRFMKELZJfi53uf4HPbWpaXE4He-y3C13aX428Fp4-BqnFye_GgCvGtzTLvJxxHGHj5560IwCd7PNv4x47TxI2z3sDE2VgQ2pZnfgbPehOxuXus1-HH_9XvzWK2_Payau3VlhVJT1XaiRgS1PUFOdX1ta8albFlPaCdZV2NFSc3aWjoheG-dMcxQ3jPFrFLKdPQafDroFt-_5uJXb31e7I0uzlmXdBDjjKu6oB__Q4c4p_K9QknOmaoZQYX6fKBsijkn1-td8luT9hoj_ZJ8mcr6mHzBP7yKzu3WdSf4GHUBHg5A6XprQhyDH92_1d0gY3BFkiDMNUKCYVyK1JgsB8aEU8XYy6rmoDTkyTy70yqTJm-DW3wJpst4OY8GT127MUm7kf4Fce6usQ</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>Kotake-Nara, Eiichi</creator><creator>Yonekura, Lina</creator><creator>Nagao, Akihiko</creator><general>Japan Oil Chemists' Society</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope></search><sort><creationdate>2015</creationdate><title>Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells</title><author>Kotake-Nara, Eiichi ; Yonekura, Lina ; Nagao, Akihiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c688t-bd69020bf20e8df9c94577b4f23d74d9183294b97e665fceaa4a35f484c888ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Bioavailability</topic><topic>Biological Availability</topic><topic>Caco-2</topic><topic>Caco-2 Cells</topic><topic>Dietary Supplements</topic><topic>fucoxanthin</topic><topic>glyceroglycolipid</topic><topic>Glycolipids - pharmacology</topic><topic>Human</topic><topic>Humans</topic><topic>intestinal absorption</topic><topic>Intestinal Absorption - drug effects</topic><topic>Micelles</topic><topic>mixed micelles</topic><topic>Secretions</topic><topic>Solubility</topic><topic>Uptakes</topic><topic>Xanthophylls - chemistry</topic><topic>Xanthophylls - metabolism</topic><toplevel>online_resources</toplevel><creatorcontrib>Kotake-Nara, Eiichi</creatorcontrib><creatorcontrib>Yonekura, Lina</creatorcontrib><creatorcontrib>Nagao, Akihiko</creatorcontrib><creatorcontrib>National Food Research Institute</creatorcontrib><creatorcontrib>National Agriculture and Food Research Organization</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><jtitle>Journal of Oleo Science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kotake-Nara, Eiichi</au><au>Yonekura, Lina</au><au>Nagao, Akihiko</au><aucorp>National Food Research Institute</aucorp><aucorp>National Agriculture and Food Research Organization</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells</atitle><jtitle>Journal of Oleo Science</jtitle><addtitle>J Oleo Sci</addtitle><date>2015</date><risdate>2015</risdate><volume>64</volume><issue>11</issue><spage>1207</spage><epage>1211</epage><pages>1207-1211</pages><issn>1345-8957</issn><eissn>1347-3352</eissn><abstract>To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. 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subjects | Bioavailability Biological Availability Caco-2 Caco-2 Cells Dietary Supplements fucoxanthin glyceroglycolipid Glycolipids - pharmacology Human Humans intestinal absorption Intestinal Absorption - drug effects Micelles mixed micelles Secretions Solubility Uptakes Xanthophylls - chemistry Xanthophylls - metabolism |
title | Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells |
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