Lrmp and Bcat1 are Candidates for the Type I Diabetes Susceptibility Locus Idd6

Three type 1 diabetes associated regions on distal mouse chromosome 6 have recently been defined by the construction and analysis of a series of congenic strains, carrying C3H/HeJ genomic material on a NOD/Lt genetic background. Whilst NOD/Lt alleles at the most distal locus Idd6 confer susceptibili...

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Veröffentlicht in:	Autoimmunity (Chur, Switzerland) Switzerland), 2003-06, Vol.36 (4), p.241-246
Hauptverfasser:	Grimm, Christina H., Rogner, Ute C., Avner, Philip
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Candidate gene Chromosome Mapping Diabetes Mellitus, Type 1 - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Genetic Predisposition to Disease - genetics Humans Insulin dependent diabetes mellitus Medical sciences Membrane Proteins - genetics Membrane Proteins - immunology Mice Mice, Inbred BALB C Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred NOD Non Obese Diabetic mouse (NOD) Polymorphism Polymorphism, Single Nucleotide Proteins - genetics Proteins - immunology Reverse Transcriptase Polymerase Chain Reaction RNA - chemistry RNA - genetics Sequence Analysis, DNA Transaminases
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