Agminated cellular blue naevi of the penis: dermoscopic, confocal and histopathological correlation of two cases
Summary Blue naevi may present rarely as multiple lesions grouped in a circumscribed area, described as agminated blue naevi. This clinical presentation may mimic metastatic malignant melanoma. We present two cases of agminated cellular blue naevi of the penis, with dermoscopy, reflectance confocal...
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Veröffentlicht in: | Clinical and experimental dermatology 2016-07, Vol.41 (5), p.490-494 |
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creator | Collgros, H. Vicente, A. Díaz, A. M. Rodríguez-Carunchio, L. Malvehy, J. Puig, S. |
description | Summary
Blue naevi may present rarely as multiple lesions grouped in a circumscribed area, described as agminated blue naevi. This clinical presentation may mimic metastatic malignant melanoma. We present two cases of agminated cellular blue naevi of the penis, with dermoscopy, reflectance confocal microscopy and histopathological correlation. Dermoscopy of the area showed multiple grouped lesions of homogeneous dark‐brown to blue colour. Using reflectance confocal microscopy, focusing on the bluish areas, predominantly bright dendritic cells were visible at the dermoepidermal junction and papillary dermis, while in the brownish areas the presence of dendritic and bright cells predominated in the basal layer. Our patients are of special interest as they are the first cases, to our knowledge, reported of agminated blue naevi on the penis, studied by both dermoscopy and confocal microscopy, confirming the diagnosis with histopathological correlation. Moreover, one case represented a divided or ‘kissing’ blue naevus of the penis. |
doi_str_mv | 10.1111/ced.12798 |
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Blue naevi may present rarely as multiple lesions grouped in a circumscribed area, described as agminated blue naevi. This clinical presentation may mimic metastatic malignant melanoma. We present two cases of agminated cellular blue naevi of the penis, with dermoscopy, reflectance confocal microscopy and histopathological correlation. Dermoscopy of the area showed multiple grouped lesions of homogeneous dark‐brown to blue colour. Using reflectance confocal microscopy, focusing on the bluish areas, predominantly bright dendritic cells were visible at the dermoepidermal junction and papillary dermis, while in the brownish areas the presence of dendritic and bright cells predominated in the basal layer. Our patients are of special interest as they are the first cases, to our knowledge, reported of agminated blue naevi on the penis, studied by both dermoscopy and confocal microscopy, confirming the diagnosis with histopathological correlation. Moreover, one case represented a divided or ‘kissing’ blue naevus of the penis.</description><identifier>ISSN: 0307-6938</identifier><identifier>EISSN: 1365-2230</identifier><identifier>DOI: 10.1111/ced.12798</identifier><identifier>PMID: 26801517</identifier><identifier>CODEN: CEDEDE</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Aged ; Dermoscopy ; Humans ; Male ; Microscopes ; Microscopy ; Microscopy, Confocal ; Nevus, Blue - pathology ; Penile Neoplasms - pathology ; Skin Neoplasms - pathology</subject><ispartof>Clinical and experimental dermatology, 2016-07, Vol.41 (5), p.490-494</ispartof><rights>2016 British Association of Dermatologists</rights><rights>2016 British Association of Dermatologists.</rights><rights>Copyright © 2016 British Association of Dermatologists</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3918-baa1b9e378cc1cb02c38de0c3c52105ddc6a62b7bf3c9c3424caf4b8008eb4df3</citedby><cites>FETCH-LOGICAL-c3918-baa1b9e378cc1cb02c38de0c3c52105ddc6a62b7bf3c9c3424caf4b8008eb4df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26801517$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Collgros, H.</creatorcontrib><creatorcontrib>Vicente, A.</creatorcontrib><creatorcontrib>Díaz, A. M.</creatorcontrib><creatorcontrib>Rodríguez-Carunchio, L.</creatorcontrib><creatorcontrib>Malvehy, J.</creatorcontrib><creatorcontrib>Puig, S.</creatorcontrib><title>Agminated cellular blue naevi of the penis: dermoscopic, confocal and histopathological correlation of two cases</title><title>Clinical and experimental dermatology</title><addtitle>Clin Exp Dermatol</addtitle><description>Summary
Blue naevi may present rarely as multiple lesions grouped in a circumscribed area, described as agminated blue naevi. This clinical presentation may mimic metastatic malignant melanoma. We present two cases of agminated cellular blue naevi of the penis, with dermoscopy, reflectance confocal microscopy and histopathological correlation. Dermoscopy of the area showed multiple grouped lesions of homogeneous dark‐brown to blue colour. Using reflectance confocal microscopy, focusing on the bluish areas, predominantly bright dendritic cells were visible at the dermoepidermal junction and papillary dermis, while in the brownish areas the presence of dendritic and bright cells predominated in the basal layer. Our patients are of special interest as they are the first cases, to our knowledge, reported of agminated blue naevi on the penis, studied by both dermoscopy and confocal microscopy, confirming the diagnosis with histopathological correlation. Moreover, one case represented a divided or ‘kissing’ blue naevus of the penis.</description><subject>Adolescent</subject><subject>Aged</subject><subject>Dermoscopy</subject><subject>Humans</subject><subject>Male</subject><subject>Microscopes</subject><subject>Microscopy</subject><subject>Microscopy, Confocal</subject><subject>Nevus, Blue - pathology</subject><subject>Penile Neoplasms - pathology</subject><subject>Skin Neoplasms - pathology</subject><issn>0307-6938</issn><issn>1365-2230</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1u1DAURi0EokNhwQsgS2xAIq1_kjjprhrKgDSCBYOQurHsm5uOSxIHO6H07fHMdFgg4Y2lq3OP7O8j5CVnZzydc8DmjAtVV4_IgsuyyISQ7DFZMMlUVtayOiHPYrxljEuuiqfkRJQV4wVXCzJe3vRuMBM2FLDr5s4EarsZ6WDwl6O-pdMW6YiDixe0wdD7CH508I6CH1oPpqNmaOjWxcmPZtr6zt-43RR8CNiZyflhb7nzFEzE-Jw8aU0X8cXDfUq-fbjaLD9m6y-rT8vLdQay5lVmjeG2RqkqAA6WCZBVgwwkFIKzommgNKWwyrYSapC5yMG0ua0Yq9DmTStPyZuDdwz-54xx0r2Luy-aAf0cNU9x1XUuijKhr_9Bb_0chvS6PcVLUdUiUW8PFAQfY8BWj8H1JtxrzvSuBp1q0PsaEvvqwTjbPk2P5DH3BJwfgDvX4f3_TXp59f6ozA4bKWn8_XfDhB-6VFIV-vvnlb7-KtcrtbnWG_kHYvWiGQ</recordid><startdate>201607</startdate><enddate>201607</enddate><creator>Collgros, H.</creator><creator>Vicente, A.</creator><creator>Díaz, A. M.</creator><creator>Rodríguez-Carunchio, L.</creator><creator>Malvehy, J.</creator><creator>Puig, S.</creator><general>Blackwell Publishing Ltd</general><general>Oxford University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201607</creationdate><title>Agminated cellular blue naevi of the penis: dermoscopic, confocal and histopathological correlation of two cases</title><author>Collgros, H. ; Vicente, A. ; Díaz, A. M. ; Rodríguez-Carunchio, L. ; Malvehy, J. ; Puig, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3918-baa1b9e378cc1cb02c38de0c3c52105ddc6a62b7bf3c9c3424caf4b8008eb4df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Aged</topic><topic>Dermoscopy</topic><topic>Humans</topic><topic>Male</topic><topic>Microscopes</topic><topic>Microscopy</topic><topic>Microscopy, Confocal</topic><topic>Nevus, Blue - pathology</topic><topic>Penile Neoplasms - pathology</topic><topic>Skin Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Collgros, H.</creatorcontrib><creatorcontrib>Vicente, A.</creatorcontrib><creatorcontrib>Díaz, A. M.</creatorcontrib><creatorcontrib>Rodríguez-Carunchio, L.</creatorcontrib><creatorcontrib>Malvehy, J.</creatorcontrib><creatorcontrib>Puig, S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Collgros, H.</au><au>Vicente, A.</au><au>Díaz, A. M.</au><au>Rodríguez-Carunchio, L.</au><au>Malvehy, J.</au><au>Puig, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Agminated cellular blue naevi of the penis: dermoscopic, confocal and histopathological correlation of two cases</atitle><jtitle>Clinical and experimental dermatology</jtitle><addtitle>Clin Exp Dermatol</addtitle><date>2016-07</date><risdate>2016</risdate><volume>41</volume><issue>5</issue><spage>490</spage><epage>494</epage><pages>490-494</pages><issn>0307-6938</issn><eissn>1365-2230</eissn><coden>CEDEDE</coden><abstract>Summary
Blue naevi may present rarely as multiple lesions grouped in a circumscribed area, described as agminated blue naevi. This clinical presentation may mimic metastatic malignant melanoma. We present two cases of agminated cellular blue naevi of the penis, with dermoscopy, reflectance confocal microscopy and histopathological correlation. Dermoscopy of the area showed multiple grouped lesions of homogeneous dark‐brown to blue colour. Using reflectance confocal microscopy, focusing on the bluish areas, predominantly bright dendritic cells were visible at the dermoepidermal junction and papillary dermis, while in the brownish areas the presence of dendritic and bright cells predominated in the basal layer. Our patients are of special interest as they are the first cases, to our knowledge, reported of agminated blue naevi on the penis, studied by both dermoscopy and confocal microscopy, confirming the diagnosis with histopathological correlation. Moreover, one case represented a divided or ‘kissing’ blue naevus of the penis.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26801517</pmid><doi>10.1111/ced.12798</doi><tpages>5</tpages></addata></record> |
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source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
subjects | Adolescent Aged Dermoscopy Humans Male Microscopes Microscopy Microscopy, Confocal Nevus, Blue - pathology Penile Neoplasms - pathology Skin Neoplasms - pathology |
title | Agminated cellular blue naevi of the penis: dermoscopic, confocal and histopathological correlation of two cases |
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