Efficacy and possible mechanisms of topical tranexamic acid in melasma

Summary Background Tranexamic acid (TA) has been suggested as an effective treatment for melasma. Aim To investigate the effects and mechanism of action of topical TA in the treatment of melasma. Methods In this study, 23 participants with melasma applied a 2% TA formulation to the whole face for 12...

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Veröffentlicht in:	Clinical and experimental dermatology 2016-07, Vol.41 (5), p.480-485
Hauptverfasser:	Kim, S. J., Park, J.-Y., Shibata, T., Fujiwara, R., Kang, H. Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antifibrinolytic Agents - therapeutic use Biomarkers - metabolism Endothelin-1 - metabolism Female Humans Immunohistochemistry Melanosis - drug therapy Melanosis - metabolism Melanosis - pathology Middle Aged Severity of Illness Index Tranexamic Acid - therapeutic use Vascular Endothelial Growth Factor A - metabolism
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