Identifying patients with type 2 diabetes in which basal supported oral therapy may not be the optimal treatment strategy

Highlights • Predictors for discontinuation of basal supported oral therapy in type 2 diabetes patients. • Data from the German DIabetes Versorgungs-Evaluation (DIVE) registry. • Higher BMI, shorter diabetes duration, and higher HbA1c predict BOT failure.

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Bibliographische Detailangaben
Veröffentlicht in:	Diabetes research and clinical practice 2016-06, Vol.116, p.127-135
Hauptverfasser:	Bramlage, Peter, Bluhmki, Tobias, Rathmann, Wolfgang, Kaltheuner, Matthias, Beyersmann, Jan, Danne, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Aged, 80 and over Basal Blood Glucose Cox proportional hazards model Diabetes Mellitus, Type 2 - drug therapy Endocrinology & Metabolism Female Glycaemic control Glycated Hemoglobin A - analysis Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use Insulin Insulin - therapeutic use Male Middle Aged Multivariate Analysis Oral antidiabetic drugs Proportional Hazards Models Time Factors
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Beschreibung
Zusammenfassung:	Highlights • Predictors for discontinuation of basal supported oral therapy in type 2 diabetes patients. • Data from the German DIabetes Versorgungs-Evaluation (DIVE) registry. • Higher BMI, shorter diabetes duration, and higher HbA1c predict BOT failure.
ISSN:	0168-8227 1872-8227
DOI:	10.1016/j.diabres.2016.03.015