Multiparameter analysis of naevi and primary melanomas identifies a subset of naevi with elevated markers of transformation

Summary Here we have carried out a multiparameter analysis using a panel of 28 immunohistochemical markers to identify markers of transformation from benign and dysplastic naevus to primary melanoma in three separate cohorts totalling 279 lesions. We have identified a set of eight markers that disti...

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Veröffentlicht in:	Pigment cell and melanoma research 2016-07, Vol.29 (4), p.444-452
Hauptverfasser:	Fox, Carly, Lambie, Duncan, Wilmott, James S., Pinder, Alex, Pavey, Sandra, Lê Cao, Kim-Anh, Akalin, Taner, Karaarslan, Isil Kilinc, Ozdemir, Fezal, Scolyer, Richard A., Yamada, Miko, Soyer, H Peter, Schaider, Helmut, Gabrielli, Brian
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - metabolism Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Humans markers Melanoma Melanoma - metabolism Melanoma - pathology naevi Nevus, Pigmented - metabolism Nevus, Pigmented - pathology Prognosis Skin Neoplasms - metabolism Skin Neoplasms - pathology Tissue Array Analysis transformation
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