Cyclodextrin-poloxamer aggregates as nanocarriers in eye drop formulations: dexamethasone and amphotericin B

In this present study cyclodextrin (CD)-poloxamer aggregates were characterized and developed as ophthalmic drug carriers. The combined effect of γCD/2-hydroxypropyl-γCD (HPγCD) mixtures and poloxamer on solubilization and permeability of two model drugs, dexamethasone (Dex) and amphotericin B (AmB)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug development and industrial pharmacy 2016-09, Vol.42 (9), p.1446-1454
Hauptverfasser:	Jansook, Phatsawee, Pichayakorn, Wiwat, Muankaew, Chutimon, Loftsson, Thorsteinn
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggregate amphotericin B Amphotericin B - chemistry Chemistry, Pharmaceutical - methods cyclodextrin Cyclodextrins - chemistry dexamethasone Dexamethasone - chemistry Drug Carriers - chemistry Drug Delivery Systems - methods eye drop gamma-Cyclodextrins - chemistry Nanoparticles - chemistry Ophthalmic Solutions - chemistry Particle Size Permeability poloxamer Poloxamer - chemistry Solubility Suspensions - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!