Fresh frozen plasma versus prothrombin complex concentrate in patients with intracranial haemorrhage related to vitamin K antagonists (INCH): a randomised trial

Summary Background Haematoma expansion is a major cause of mortality in intracranial haemorrhage related to vitamin K antagonists (VKA-ICH). Normalisation of the international normalised ratio (INR) is recommended, but optimum haemostatic management is controversial. We assessed the safety and effic...

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Veröffentlicht in:	Lancet neurology 2016-05, Vol.15 (6), p.566-573
Hauptverfasser:	Steiner, Thorsten, Prof, Poli, Sven, MD, Griebe, Martin, MD, Hüsing, Johannes, Hajda, Jacek, MD, Freiberger, Anja, Bendszus, Martin, Prof, Bösel, Julian, Prof, Christensen, Hanne, Prof, Dohmen, Christian, Prof, Hennerici, Michael, Prof, Kollmer, Jennifer, MD, Stetefeld, Henning, MD, Wartenberg, Katja E, MD, Weimar, Christian, Prof, Hacke, Werner, Prof, Veltkamp, Roland, Prof
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anticoagulants - adverse effects Blood Coagulation Factors - administration & dosage Blood Coagulation Factors - pharmacology Blood Component Transfusion - adverse effects Blood Component Transfusion - methods Clinical outcomes Female Hemophilia Humans International Normalized Ratio Intracranial Hemorrhages - chemically induced Male Medical imaging Mortality Neurology Outcome Assessment (Health Care) Plasma Single-Blind Method Stroke Thrombosis Vitamin K - antagonists & inhibitors
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