Monoiodoacetic acid induces arthritis and synovitis in rats in a dose- and time-dependent manner: proposed model-specific scoring systems

Summary Objective In a rat monoiodoacetic acid (MIA)-induced arthritis model, the amount of MIA commonly used was too high, resulting in rapid bone destruction. We examined the effect of MIA concentrations on articular cartilage and infrapatellar fat pad (IFP). We also established an original system...

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Veröffentlicht in:	Osteoarthritis and cartilage 2016-07, Vol.24 (7), p.1284-1291
Hauptverfasser:	Udo, Mio, Muneta, Takeshi, Tsuji, Kunikazu, Ozeki, Nobutake, Nakagawa, Yusuke, Ohara, Toshiyuki, Saito, Ryusuke, Yanagisawa, Katsuaki, Koga, Hideyuki, Sekiya, Ichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cartilage degeneration Cartilage, Articular Injections, Intra-Articular Iodoacetic Acid Male Monoiodoacetic acid Osteoarthritis Rat Rats Rats, Wistar Rheumatology Scoring system Synovitis
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