Chidamide alleviates TGF-β-induced epithelial–mesenchymal transition in lung cancer cell lines

Transforming growth factor-β (TGF-β)-induced epithelial–mesenchymal transition is a critical process in the initiation of metastasis of various types of cancer. Chidamide is a class I histone deacetylase inhibitor with anti-tumor activity. This study investigated the effects of chidamide on TGF-β-me...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biology reports 2016-07, Vol.43 (7), p.687-695
Hauptverfasser:	Lin, Sheng-Hao, Wang, Bing-Yen, Lin, Ching-Hsiung, Chien, Peng-Ju, Wu, Yueh-Feng, Ko, Jiunn-Liang, Chen, Jeremy J. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Aminopyridines - pharmacology Animal Anatomy Animal Biochemistry Antineoplastic Agents - pharmacology Benzamides - pharmacology Biomedical and Life Sciences Cadherins - genetics Cadherins - metabolism DNA Methylation Drug Screening Assays, Antitumor Epigenesis, Genetic Epithelial-Mesenchymal Transition - drug effects Gene Expression Gene Expression Regulation, Neoplastic Histology Histone Deacetylase Inhibitors - pharmacology Humans Life Sciences Lung Neoplasms - drug therapy Lung Neoplasms - pathology Morphology Original Article Phosphorylation Promoter Regions, Genetic Protein Processing, Post-Translational Transforming Growth Factor beta - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!