Laser surgery as a treatment for histologically confirmed sarcoids in the horse

Summary Reasons for performing study Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long‐term follow‐up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to pr...

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Veröffentlicht in:Equine veterinary journal 2016-07, Vol.48 (4), p.451-456
Hauptverfasser: Compston, P. C., Turner, T., Wylie, C. E., Payne, R. J.
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container_end_page 456
container_issue 4
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container_title Equine veterinary journal
container_volume 48
creator Compston, P. C.
Turner, T.
Wylie, C. E.
Payne, R. J.
description Summary Reasons for performing study Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long‐term follow‐up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to provide a definitive histological diagnosis of sarcoid. Objectives To establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids and evaluate risk factors for recurrence. Study design Retrospective time‐to‐event analysis. Methods Horses included had laser surgery to remove at least one sarcoid between 1 July 2005 and 1 September 2012. No previous known/concurrent veterinary treatment was administered. Diagnosis was confirmed by histology in all cases. Clinical data were retrieved from the hospital database. Follow‐up information was obtained by telephone questionnaire. Results Ninety‐nine horses, with a total of 235 sarcoids, were included in the analysis; 82 (83%) had no recurrence of the sarcoid removed and 71 (72%) had no occurrence of any sarcoids following surgery. Horses with sarcoids on the head and neck and those with verrucose sarcoids were at increased risk of recurrence (hazard ratios of 1.61 and 4.03, and 95% confidence intervals of 1.02–2.56 and 1.11–14.7, respectively). Conclusions Laser resection of sarcoids in the horse has a positive post operative prognosis. Further work is required to fully evaluate risk factors for recurrence fully.
doi_str_mv 10.1111/evj.12456
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C. ; Turner, T. ; Wylie, C. E. ; Payne, R. J.</creator><creatorcontrib>Compston, P. C. ; Turner, T. ; Wylie, C. E. ; Payne, R. J.</creatorcontrib><description>Summary Reasons for performing study Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long‐term follow‐up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to provide a definitive histological diagnosis of sarcoid. Objectives To establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids and evaluate risk factors for recurrence. Study design Retrospective time‐to‐event analysis. Methods Horses included had laser surgery to remove at least one sarcoid between 1 July 2005 and 1 September 2012. No previous known/concurrent veterinary treatment was administered. Diagnosis was confirmed by histology in all cases. Clinical data were retrieved from the hospital database. Follow‐up information was obtained by telephone questionnaire. Results Ninety‐nine horses, with a total of 235 sarcoids, were included in the analysis; 82 (83%) had no recurrence of the sarcoid removed and 71 (72%) had no occurrence of any sarcoids following surgery. Horses with sarcoids on the head and neck and those with verrucose sarcoids were at increased risk of recurrence (hazard ratios of 1.61 and 4.03, and 95% confidence intervals of 1.02–2.56 and 1.11–14.7, respectively). Conclusions Laser resection of sarcoids in the horse has a positive post operative prognosis. 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C.</creatorcontrib><creatorcontrib>Turner, T.</creatorcontrib><creatorcontrib>Wylie, C. E.</creatorcontrib><creatorcontrib>Payne, R. J.</creatorcontrib><title>Laser surgery as a treatment for histologically confirmed sarcoids in the horse</title><title>Equine veterinary journal</title><addtitle>Equine Vet J</addtitle><description>Summary Reasons for performing study Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long‐term follow‐up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to provide a definitive histological diagnosis of sarcoid. Objectives To establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids and evaluate risk factors for recurrence. Study design Retrospective time‐to‐event analysis. Methods Horses included had laser surgery to remove at least one sarcoid between 1 July 2005 and 1 September 2012. No previous known/concurrent veterinary treatment was administered. Diagnosis was confirmed by histology in all cases. Clinical data were retrieved from the hospital database. Follow‐up information was obtained by telephone questionnaire. Results Ninety‐nine horses, with a total of 235 sarcoids, were included in the analysis; 82 (83%) had no recurrence of the sarcoid removed and 71 (72%) had no occurrence of any sarcoids following surgery. Horses with sarcoids on the head and neck and those with verrucose sarcoids were at increased risk of recurrence (hazard ratios of 1.61 and 4.03, and 95% confidence intervals of 1.02–2.56 and 1.11–14.7, respectively). Conclusions Laser resection of sarcoids in the horse has a positive post operative prognosis. 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J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5316-fa9ae9e4d55d18827b3b8fb1eeb924b8250b022b2f22c558a3ba409784df98313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Animals</topic><topic>Confidence intervals</topic><topic>Female</topic><topic>histology</topic><topic>horse</topic><topic>Horse Diseases - surgery</topic><topic>Horses</topic><topic>laser</topic><topic>Laser surgery</topic><topic>Laser Therapy - veterinary</topic><topic>Male</topic><topic>Proportional Hazards Models</topic><topic>Retrospective Studies</topic><topic>sarcoid</topic><topic>Skin Neoplasms - surgery</topic><topic>Skin Neoplasms - veterinary</topic><topic>Surgery</topic><topic>time-to-event analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Compston, P. C.</creatorcontrib><creatorcontrib>Turner, T.</creatorcontrib><creatorcontrib>Wylie, C. E.</creatorcontrib><creatorcontrib>Payne, R. J.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Equine veterinary journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Compston, P. C.</au><au>Turner, T.</au><au>Wylie, C. E.</au><au>Payne, R. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laser surgery as a treatment for histologically confirmed sarcoids in the horse</atitle><jtitle>Equine veterinary journal</jtitle><addtitle>Equine Vet J</addtitle><date>2016-07</date><risdate>2016</risdate><volume>48</volume><issue>4</issue><spage>451</spage><epage>456</epage><pages>451-456</pages><issn>0425-1644</issn><eissn>2042-3306</eissn><coden>EQVJAI</coden><abstract>Summary Reasons for performing study Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long‐term follow‐up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to provide a definitive histological diagnosis of sarcoid. Objectives To establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids and evaluate risk factors for recurrence. Study design Retrospective time‐to‐event analysis. Methods Horses included had laser surgery to remove at least one sarcoid between 1 July 2005 and 1 September 2012. No previous known/concurrent veterinary treatment was administered. Diagnosis was confirmed by histology in all cases. Clinical data were retrieved from the hospital database. Follow‐up information was obtained by telephone questionnaire. Results Ninety‐nine horses, with a total of 235 sarcoids, were included in the analysis; 82 (83%) had no recurrence of the sarcoid removed and 71 (72%) had no occurrence of any sarcoids following surgery. Horses with sarcoids on the head and neck and those with verrucose sarcoids were at increased risk of recurrence (hazard ratios of 1.61 and 4.03, and 95% confidence intervals of 1.02–2.56 and 1.11–14.7, respectively). Conclusions Laser resection of sarcoids in the horse has a positive post operative prognosis. Further work is required to fully evaluate risk factors for recurrence fully.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>25959259</pmid><doi>10.1111/evj.12456</doi><tpages>6</tpages></addata></record>
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subjects Animals
Confidence intervals
Female
histology
horse
Horse Diseases - surgery
Horses
laser
Laser surgery
Laser Therapy - veterinary
Male
Proportional Hazards Models
Retrospective Studies
sarcoid
Skin Neoplasms - surgery
Skin Neoplasms - veterinary
Surgery
time-to-event analysis
title Laser surgery as a treatment for histologically confirmed sarcoids in the horse
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