A Novel Gene Delivery System for Mammalian Cells

Although gene therapy holds great promise for the treatment of both acquired and genetic diseases, its development has been limited by practical considerations. Nonviral efficacy of delivery remains quite poor. We are investigating the feasibility of a novel lipid-based delivery system, cochleates,...

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Veröffentlicht in:	Anticancer research 2004-03, Vol.24 (2A), p.483-488
Hauptverfasser:	GIBSON, Brian, DUFFY, Angela M, FOGERITE, Susan Gould, KRAUSE-ELSMORE, Sara, RUYING LU, SHANG, Gaofeng, CHEN, Zi-Wei, MANNINO, Raphael J, BOUCHIER-HAYES, David J, HARMEY, Judith H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Animals Biological and medical sciences Cell Line, Tumor Gene Transfer Techniques Genes, Reporter Green Fluorescent Proteins Humans Lipid Bilayers - administration & dosage Lipid Bilayers - pharmacokinetics Luminescent Proteins - biosynthesis Luminescent Proteins - genetics Macrophages - metabolism Mammary Neoplasms, Experimental - genetics Mammary Neoplasms, Experimental - metabolism Medical sciences Mice Plasmids - administration & dosage Plasmids - genetics Rhodamines - administration & dosage Rhodamines - pharmacokinetics Transfection Transgenes Tumors
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