A case of retroperitoneal Castleman's disease with paraneoplastic pemphigus

Paraneoplastic pemphigus is a rare autoimmune bullous dermatosis, which is caused by potential neoplasm, especially the Castleman's disease. Castleman's disease associated with paraneoplastic pemphigus is misdiagnosed frequently and easily in clinical practices. Furthermore, it is reported...

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Veröffentlicht in:Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban 2016-05, Vol.41 (5), p.548-552
Hauptverfasser: Zhang, Zhipeng, Zhou, Maosong, Guo, Jin, Feng, Tiecheng, Li, Xinying, Chen, Huan, Li, Jindong
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container_end_page 552
container_issue 5
container_start_page 548
container_title Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban
container_volume 41
creator Zhang, Zhipeng
Zhou, Maosong
Guo, Jin
Feng, Tiecheng
Li, Xinying
Chen, Huan
Li, Jindong
description Paraneoplastic pemphigus is a rare autoimmune bullous dermatosis, which is caused by potential neoplasm, especially the Castleman's disease. Castleman's disease associated with paraneoplastic pemphigus is misdiagnosed frequently and easily in clinical practices. Furthermore, it is reported that the mortality rate for this disease is very high. Bronchiolitis obliterans is the most common complication and the most important cause of death. There was a female patient presenting recalcitrant mucocutaneous erosions, ulcers and scattered erythemas in the body. The patient was diagnosed and treated for pemphigus vulgaris with little success in Xiangya Hospital, Central South University in January 2015. Further investigations confirmed the diagnosis of paraneoplastic pemphigus with retroperitoneal tumor. Subsequently, the patient was treated with tumor resection in combination with intravenous immunoglobulin and corticosteroids. The pathology revealed that it was the Castleman's disease. Her mucocutaneous performance
doi_str_mv 10.11817/j.issn.1672-7347.2016.05.016
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Castleman's disease associated with paraneoplastic pemphigus is misdiagnosed frequently and easily in clinical practices. Furthermore, it is reported that the mortality rate for this disease is very high. Bronchiolitis obliterans is the most common complication and the most important cause of death. There was a female patient presenting recalcitrant mucocutaneous erosions, ulcers and scattered erythemas in the body. The patient was diagnosed and treated for pemphigus vulgaris with little success in Xiangya Hospital, Central South University in January 2015. Further investigations confirmed the diagnosis of paraneoplastic pemphigus with retroperitoneal tumor. Subsequently, the patient was treated with tumor resection in combination with intravenous immunoglobulin and corticosteroids. The pathology revealed that it was the Castleman's disease. 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subjects Adrenal Cortex Hormones - therapeutic use
Castleman Disease - complications
Castleman Disease - therapy
Female
Humans
Immunoglobulins, Intravenous - therapeutic use
Paraneoplastic Syndromes - complications
Paraneoplastic Syndromes - therapy
Pemphigus - complications
Pemphigus - therapy
Retroperitoneal Space - pathology
title A case of retroperitoneal Castleman's disease with paraneoplastic pemphigus
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